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Journal of Medicinal Chemistry
|
October 20, 2023
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease
Solomon D Kattar, Anmol Gulati, Kaila A Margrey, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
Science Translational Medicine
|
April 24, 2020
LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
Marco A S Baptista, Kalpana Merchant, Ted Barrett, et al.
Journal of Medicinal Chemistry
|
September 4, 2024
Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors
Kaitlyn M Logan, Will Kaplan, Vladimir Simov, et al.
Journal of Medicinal Chemistry
|
December 30, 2021
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
Mitchell H Keylor, Anmol Gulati, Solomon D Kattar, et al.
Journal of Medicinal Chemistry
|
March 1, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Jack D Scott, Duane E DeMong, Thomas J Greshock, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
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Search research articles
Search
Showing results (31-40 of 37) with videos related to
Sort By:
Page
of 4
You have reached the last page of results.
This site can display upto 37 results.
Journal of Medicinal Chemistry
|
October 20, 2023
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease
Solomon D Kattar, Anmol Gulati, Kaila A Margrey, et al.
Journal of Medicinal Chemistry
|
March 4, 2016
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates
Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, et al.
Science Translational Medicine
|
April 24, 2020
LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
Marco A S Baptista, Kalpana Merchant, Ted Barrett, et al.
Journal of Medicinal Chemistry
|
September 4, 2024
Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors
Kaitlyn M Logan, Will Kaplan, Vladimir Simov, et al.
Journal of Medicinal Chemistry
|
December 30, 2021
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
Mitchell H Keylor, Anmol Gulati, Solomon D Kattar, et al.
Journal of Medicinal Chemistry
|
March 1, 2017
Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity
Jack D Scott, Duane E DeMong, Thomas J Greshock, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
Page
of 4