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Proceedings of the National Academy of Sciences of the United States of America|April 4, 2018
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylaseSamuel K McBrayer, Benjamin A Olenchock, Gabriel J DiNatale, et al.Cell Reports. Medicine|November 22, 2023
Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1Yixiang Li, Navin R Mahadevan, Leslie Duplaquet, et al.Genes & Development|November 16, 2019
The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesisMatthew G Oser, Amin H Sabet, Wenhua Gao, et al.Biorxiv : the Preprint Server for Biology|July 17, 2025
EED Maintains the Small Cell Lung Cancer Neuroendocrine Phenotype and Drives Lung Cancer Histological TransformationYixiang Li, Yasmin N Laimon, Hyeonseo Cho, et al.Nature Cell Biology|August 17, 2023
KDM6A epigenetically regulates subtype plasticity in small cell lung cancerLeslie Duplaquet, Yixiang Li, Matthew A Booker, et al.Biorxiv : the Preprint Server for Biology|February 8, 2024
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancerLeslie Duplaquet, Kevin So, Alexander W Ying, et al.Cell Metabolism|February 26, 2019
Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione DepletionIsaac S Harris, Jennifer E Endress, Jonathan L Coloff, et al.Developmental Cell|August 27, 2025
Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancerDeli Hong, Ying Lyu, Richa Nayak, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 24, 2024
Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA ProfilingTalal El Zarif, Catherine B Meador, Xintao Qiu, et al.Science Advances|February 6, 2021
Targeting oncoproteins with a positive selection assay for protein degradersVidyasagar Koduri, Leslie Duplaquet, Benjamin L Lampson, et al.Pageof 4