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Matthew Holderfield

Showing results (11-20 of 31) with videos related to

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FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|March 19, 2005
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesisRichard C A Sainson, Jason Aoto, Martin N Nakatsu, et al.
Molecular Cell|November 28, 2016
Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory CircuitDaniel A Ritt, María T Abreu-Blanco, Lakshman Bindu, et al.
Cancer Cell|May 18, 2013
RAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylationMatthew Holderfield, Hanne Merritt, John Chan, et al.
Cancer Research|February 14, 2014
Vemurafenib cooperates with HPV to promote initiation of cutaneous tumorsMatthew Holderfield, Edward Lorenzana, Ben Weisburd, et al.
Science Signaling|October 4, 2018
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signalingMarco Biancucci, George Minasov, Avik Banerjee, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 26, 2021
Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 InhibitionLick Pui Lai, Viviane Brel, Kanika Sharma, et al.
Scientific Reports|November 3, 2015
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactionsWilliam K Gillette, Dominic Esposito, Maria Abreu Blanco, et al.
Cancer Discovery|June 22, 2026
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant CancersKyle J Seamon, Yongxian Zhuang, Yu Chi Yang, et al.
Cell Reports Methods|October 21, 2021
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signalingJeffrey R Whiteaker, Kanika Sharma, Melissa A Hoffman, et al.
Journal of Medicinal Chemistry|February 24, 2025
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted CancersJames Cregg, Kristof Pota, Aidan C A Tomlinson, et al.
Pageof 4

Showing results (11-20 of 31) with videos related to

Sort By:
Pageof 4
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|March 19, 2005
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesisRichard C A Sainson, Jason Aoto, Martin N Nakatsu, et al.
Molecular Cell|November 28, 2016
Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory CircuitDaniel A Ritt, María T Abreu-Blanco, Lakshman Bindu, et al.
Cancer Cell|May 18, 2013
RAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylationMatthew Holderfield, Hanne Merritt, John Chan, et al.
Cancer Research|February 14, 2014
Vemurafenib cooperates with HPV to promote initiation of cutaneous tumorsMatthew Holderfield, Edward Lorenzana, Ben Weisburd, et al.
Science Signaling|October 4, 2018
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signalingMarco Biancucci, George Minasov, Avik Banerjee, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 26, 2021
Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 InhibitionLick Pui Lai, Viviane Brel, Kanika Sharma, et al.
Scientific Reports|November 3, 2015
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactionsWilliam K Gillette, Dominic Esposito, Maria Abreu Blanco, et al.
Cancer Discovery|June 22, 2026
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant CancersKyle J Seamon, Yongxian Zhuang, Yu Chi Yang, et al.
Cell Reports Methods|October 21, 2021
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signalingJeffrey R Whiteaker, Kanika Sharma, Melissa A Hoffman, et al.
Journal of Medicinal Chemistry|February 24, 2025
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted CancersJames Cregg, Kristof Pota, Aidan C A Tomlinson, et al.
Pageof 4