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Bioorganic & Medicinal Chemistry Letters|November 27, 2015
Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonistsMaria-Jesus Blanco, Tatiana Vetman, Srinivasan Chandrasekhar, et al.Bioorganic & Medicinal Chemistry Letters|August 23, 2005
Privileged structure-based ligands for melanocortin receptors-tetrahydroquinolines, indoles, and aminotetralinesMatthew J Fisher, Ryan T Backer, Saba Husain, et al.Bioorganic & Medicinal Chemistry Letters|May 16, 2006
Privileged structure based ligands for melanocortin receptors--4,4-disubstituted piperidine derivativesSteven L Kuklish, Ryan T Backer, Karin Briner, et al.Bioorganic & Medicinal Chemistry Letters|May 3, 2006
Privileged structure based ligands for melanocortin-4 receptors--aliphatic piperazine derivativesKarin Briner, Iván Collado, Matthew J Fisher, et al.Bioorganic & Medicinal Chemistry Letters|January 15, 2016
Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profileMaria-Jesus Blanco, Tatiana Vetman, Srinivasan Chandrasekhar, et al.Journal of Medicinal Chemistry|February 10, 2018
Identification and Mitigation of Reactive Metabolites of 2-Aminoimidazole-Containing Microsomal Prostaglandin E Synthase-1 Inhibitors Terminated Due to Clinical Drug-Induced Liver InjuryBryan H Norman, Matthew J Fisher, Matthew A Schiffler, et al.Bioorganic & Medicinal Chemistry Letters|March 30, 2016
Identification and biological activity of 6-alkyl-substituted 3-methyl-pyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonistsMaria-Jesus Blanco, Tatiana Vetman, Srinivasan Chandrasekhar, et al.The Journal of Pharmacology and Experimental Therapeutics|January 8, 2016
Identification and Characterization of Novel Microsomal Prostaglandin E Synthase-1 Inhibitors for AnalgesiaSrinivasan Chandrasekhar, Anita K Harvey, Xiao-Peng Yu, et al.Journal of Medicinal Chemistry|May 12, 2015
Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory TherapeuticsJohn Gately Luz, Stephen Antonysamy, Steven L Kuklish, et al.Drug Safety|April 5, 2013
Results from the first decade of research conducted by the Research on Adverse Drug Events and Reports (RADAR) projectJune M McKoy, Matthew J Fisher, D Mark Courtney, et al.Pageof 4