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Cancer Chemotherapy and Pharmacology|July 5, 2015
Integrated nonclinical and clinical risk assessment of the investigational proteasome inhibitor ixazomib on the QTc interval in cancer patientsNeeraj Gupta, Yeamin Huh, Matthew M Hutmacher, et al.Journal of Clinical Pharmacology|January 18, 2008
Performance characteristics for some typical QT study designs under the ICH E-14 guidanceMatthew M Hutmacher, Sunny Chapel, Marilyn A Agin, et al.Clinical Ophthalmology (Auckland, N.Z.)|March 4, 2015
Population pharmacokinetics of pegaptanib sodium (Macugen(®)) in patients with diabetic macular edemaAnthony S Basile, Matthew M Hutmacher, Kenneth G Kowalski, et al.Journal of Clinical Pharmacology|August 14, 2014
Population dose-response analysis of daily seizure count following vigabatrin therapy in adult and pediatric patients with refractory complex partial seizuresJace C Nielsen, Matthew M Hutmacher, David L Wesche, et al.Plos One|September 17, 2013
Predicting relapsing-remitting dynamics in multiple sclerosis using discrete distribution models: a population approachNieves Velez de Mendizabal, Matthew M Hutmacher, Iñaki F Troconiz, et al.Arthritis Research & Therapy|July 27, 2014
Changes in serum creatinine in patients with active rheumatoid arthritis treated with tofacitinib: results from clinical trialsJohn D Isaacs, Andrea Zuckerman, Sriram Krishnaswami, et al.Psychopharmacology|June 8, 2011
Translational PK-PD modelling of molecular target modulation for the AMPA receptor positive allosteric modulator Org 26576Roberta Bursi, Gul Erdemli, Robert Campbell, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 2, 2007
Central nervous system pharmacokinetics of the Mdr1 P-glycoprotein substrate CP-615,003: intersite differences and implications for human receptor occupancy projections from cerebrospinal fluid exposuresKarthik Venkatakrishnan, Elaine Tseng, Frederick R Nelson, et al.British Journal of Clinical Pharmacology|August 18, 2016
Comparative assessment of clinical response in patients with rheumatoid arthritis between PF-05280586, a proposed rituximab biosimilar, and rituximabJason H Williams, Matthew M Hutmacher, Matthew L Zierhut, et al.Plos One|December 3, 2020
Complex genetic dependencies among growth and neurological phenotypes in healthy children: Towards deciphering developmental mechanismsLisa Uechi, Mahjoubeh Jalali, Jayson D Wilbur, et al.Pageof 4