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Journal of Medicinal Chemistry|June 7, 2017
The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate ReceptorsKatie L Strong, Matthew P Epplin, John Bacsa, et al.
Journal of Medicinal Chemistry|June 16, 2020
Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) ReceptorMatthew P Epplin, Ayush Mohan, Lynnea D Harris, et al.
Elife|May 25, 2018
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groupsRiley Perszyk, Brooke M Katzman, Hirofumi Kusumoto, et al.
The Journal of Physiology|June 25, 2025
Selective enhancement of the interneuron network and gamma-band power via GluN2C/GluN2D NMDA receptor potentiationChad R Camp, Tue G Banke, Hao Xing, et al.
Biorxiv : the Preprint Server for Biology|November 22, 2024
Selective Enhancement of the Interneuron Network and Gamma-Band Power via GluN2C/GluN2D NMDA Receptor PotentiationChad R Camp, Tue G Banke, Hao Xing, et al.
Molecular Pharmacology|December 16, 2017
The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA ReceptorThomas M Kaiser, Steven A Kell, Hirofumi Kusumoto, et al.
Neuropharmacology|May 12, 2020
Negative allosteric modulation of GluN1/GluN3 NMDA receptorsZongjian Zhu, Feng Yi, Matthew P Epplin, et al.
Nature Chemical Biology|January 22, 2020
Biased modulators of NMDA receptors control channel opening and ion selectivityRiley E Perszyk, Sharon A Swanger, Chris Shelley, et al.
ACS Chemical Neuroscience|December 16, 2020
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate ReceptorsKatie L Strong, Matthew P Epplin, Kevin K Ogden, et al.
Biorxiv : the Preprint Server for Biology|December 31, 2025
Discrete interneuron subsets participate in GluN1/GluN3A excitatory glycine receptor (eGlyR)-mediated regulation of hippocampal network activity throughout development and evolutionJune Hoan Kim, Anna Vlachos, Vivek Mahadevan, et al.
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