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Human Molecular Genetics|August 1, 2025
Huntingtin reduction results in altered nuclear structure and heterochromatic instabilityJessica C Barron, Sean T Coady, Abigayle C Fleming, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 28, 2008
Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicityCatherine M Cowan, Mannie M Y Fan, Jing Fan, et al.
Molecular and Cellular Neurosciences|March 23, 2004
Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's diseaseMelinda M Zeron, Herman B Fernandes, Claudia Krebs, et al.
Journal of Neurochemistry|January 19, 2006
Wild-type huntingtin protects neurons from excitotoxicityBlair R Leavitt, Jeremy M van Raamsdonk, Jacqueline Shehadeh, et al.
Eneuro|May 28, 2026
Striatal neuron excitability is regulated by huntingtin in the adult brainJessica C Barron, Meghan L Greenland, Samantha J Carew, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 24, 2012
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neuronsAlexandra M Kaufman, Austen J Milnerwood, Marja D Sepers, et al.
Neurobiology of Disease|October 19, 2005
Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse modelsRona K Graham, Elizabeth J Slow, Yu Deng, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|March 21, 2023
Axonal ER Ca2+ Release Selectively Enhances Activity-Independent Glutamate Release in a Huntington Disease ModelJames P Mackay, Amy I Smith-Dijak, Ellen T Koch, et al.
Neurobiology of Disease|January 24, 2025
Huntingtin plays an essential role in the adult hippocampusJessica C Barron, Laura J Dawson, Samantha J Carew, et al.
Neurobiology of Disease|April 23, 2022
Altered cortical processing of sensory input in Huntington disease mouse modelsMarja D Sepers, James P Mackay, Ellen Koch, et al.
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