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Matthew R Lee

Showing results (51-60 of 81) with videos related to

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Journal of Medicinal Chemistry|August 18, 2010
Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitorsBin Wu, Hui-Ling Wang, Liping Pettus, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease|August 20, 2025
Post-translational modifications of huntingtin's N17 region: implications for self-association and membrane bindingMariana Gallo, Raffaele Ingenito, Marco Finotto, et al.
Bioorganic & Medicinal Chemistry Letters|June 17, 2008
Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseasesNing Chen, Roland W Bürli, Susana Neira, et al.
Chemical Research in Toxicology|January 26, 2010
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screeningRaju Subramanian, Matthew R Lee, John G Allen, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2015
Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitorsBin Wu, Hui-Ling Wang, Victor J Cee, et al.
Bioorganic & Medicinal Chemistry Letters|January 19, 2015
The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitorsHui-Ling Wang, Victor J Cee, Frank Chavez, et al.
Journal of Medicinal Chemistry|March 12, 2010
Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinaseLiping H Pettus, Ryan P Wurz, Shimin Xu, et al.
Bioorganic & Medicinal Chemistry|April 18, 2016
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profilingLongbin Liu, Matthew R Lee, Joseph L Kim, et al.
Bioorganic & Medicinal Chemistry|May 29, 2016
Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234]Longbin Liu, Matthew R Lee, Joseph L Kim, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeuticsQingping Zeng, Matthew P Bourbeau, G Erich Wohlhieter, et al.
Pageof 9

Showing results (51-60 of 81) with videos related to

Sort By:
Pageof 9
Journal of Medicinal Chemistry|August 18, 2010
Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitorsBin Wu, Hui-Ling Wang, Liping Pettus, et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease|August 20, 2025
Post-translational modifications of huntingtin's N17 region: implications for self-association and membrane bindingMariana Gallo, Raffaele Ingenito, Marco Finotto, et al.
Bioorganic & Medicinal Chemistry Letters|June 17, 2008
Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseasesNing Chen, Roland W Bürli, Susana Neira, et al.
Chemical Research in Toxicology|January 26, 2010
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screeningRaju Subramanian, Matthew R Lee, John G Allen, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2015
Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitorsBin Wu, Hui-Ling Wang, Victor J Cee, et al.
Bioorganic & Medicinal Chemistry Letters|January 19, 2015
The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitorsHui-Ling Wang, Victor J Cee, Frank Chavez, et al.
Journal of Medicinal Chemistry|March 12, 2010
Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinaseLiping H Pettus, Ryan P Wurz, Shimin Xu, et al.
Bioorganic & Medicinal Chemistry|April 18, 2016
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profilingLongbin Liu, Matthew R Lee, Joseph L Kim, et al.
Bioorganic & Medicinal Chemistry|May 29, 2016
Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234]Longbin Liu, Matthew R Lee, Joseph L Kim, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeuticsQingping Zeng, Matthew P Bourbeau, G Erich Wohlhieter, et al.
Pageof 9