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Matthew R Lee

Showing results (61-70 of 81) with videos related to

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Journal of Medicinal Chemistry|September 22, 2009
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinolineAdrian L Smith, Frenel F DeMorin, Nick A Paras, et al.
Biochimica Et Biophysica Acta. General Subjects|November 27, 2020
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)Joseph D Ho, Matthew R Lee, Charles T Rauch, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancerQingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry|September 27, 2008
3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinaseLiping H Pettus, Shimin Xu, Guo-Qiang Cao, et al.
Bioorganic & Medicinal Chemistry Letters|October 23, 2016
Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitorsRyan P Wurz, Christine Sastri, Derin C D'Amico, et al.
Journal of Medicinal Chemistry|September 27, 2008
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffoldBrad Herberich, Guo-Qiang Cao, Partha P Chakrabarti, et al.
Journal of Medicinal Chemistry|July 11, 2022
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's DiseaseTammy Ladduwahetty, Matthew R Lee, Michel C Maillard, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Pageof 9

Showing results (61-70 of 81) with videos related to

Sort By:
Pageof 9
Journal of Medicinal Chemistry|September 22, 2009
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinolineAdrian L Smith, Frenel F DeMorin, Nick A Paras, et al.
Biochimica Et Biophysica Acta. General Subjects|November 27, 2020
Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)Joseph D Ho, Matthew R Lee, Charles T Rauch, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancerQingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry|September 27, 2008
3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinaseLiping H Pettus, Shimin Xu, Guo-Qiang Cao, et al.
Bioorganic & Medicinal Chemistry Letters|October 23, 2016
Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitorsRyan P Wurz, Christine Sastri, Derin C D'Amico, et al.
Journal of Medicinal Chemistry|September 27, 2008
Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffoldBrad Herberich, Guo-Qiang Cao, Partha P Chakrabarti, et al.
Journal of Medicinal Chemistry|July 11, 2022
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's DiseaseTammy Ladduwahetty, Matthew R Lee, Michel C Maillard, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Pageof 9