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Journal of Medicinal Chemistry
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September 4, 2008
Design, synthesis, and biological evaluation of potent c-Met inhibitors
Noel D D'Angelo, Steven F Bellon, Shon K Booker, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 21, 2015
The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors
Ryan P Wurz, Liping H Pettus, Claire Jackson, et al.
Journal of Medicinal Chemistry
|
October 27, 2017
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model
Kevin R Fales, F George Njoroge, Harold B Brooks, et al.
ACS Medicinal Chemistry Letters
|
April 21, 2016
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors
Victor J Cee, Frank Chavez, Bradley Herberich, et al.
Nature Communications
|
April 27, 2018
Structural basis for GPR40 allosteric agonism and incretin stimulation
Joseph D Ho, Betty Chau, Logan Rodgers, et al.
Scientific Reports
|
October 20, 2018
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models
Harold B Brooks, Timothy I Meier, Sandaruwan Geeganage, et al.
Nature Medicine
|
November 8, 2016
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, et al.
Journal of Medicinal Chemistry
|
June 11, 2016
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors
Liping H Pettus, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
January 10, 2019
Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies
Hui-Ling Wang, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
August 5, 2021
[<sup>11</sup>C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Page
of 9
Search research articles
Search
Showing results (71-80 of 81) with videos related to
Sort By:
Page
of 9
Journal of Medicinal Chemistry
|
September 4, 2008
Design, synthesis, and biological evaluation of potent c-Met inhibitors
Noel D D'Angelo, Steven F Bellon, Shon K Booker, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 21, 2015
The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors
Ryan P Wurz, Liping H Pettus, Claire Jackson, et al.
Journal of Medicinal Chemistry
|
October 27, 2017
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model
Kevin R Fales, F George Njoroge, Harold B Brooks, et al.
ACS Medicinal Chemistry Letters
|
April 21, 2016
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors
Victor J Cee, Frank Chavez, Bradley Herberich, et al.
Nature Communications
|
April 27, 2018
Structural basis for GPR40 allosteric agonism and incretin stimulation
Joseph D Ho, Betty Chau, Logan Rodgers, et al.
Scientific Reports
|
October 20, 2018
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models
Harold B Brooks, Timothy I Meier, Sandaruwan Geeganage, et al.
Nature Medicine
|
November 8, 2016
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, et al.
Journal of Medicinal Chemistry
|
June 11, 2016
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors
Liping H Pettus, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
January 10, 2019
Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies
Hui-Ling Wang, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
August 5, 2021
[<sup>11</sup>C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
Longbin Liu, Peter D Johnson, Michael E Prime, et al.
Page
of 9