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Bioorganic Chemistry
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March 10, 2021
Synthesis, biological evaluation and molecular docking studies of indeno [1, 2-c] pyrazol derivatives as inhibitors of mitochondrial malate dehydrogenase 2 (MDH2)
Farzaneh Ahmadi, Matthias Engel, Mehdi M Baradarani
Archiv Der Pharmazie
|
July 19, 2023
Targeting the binding pocket of the fluorophore 8-anilinonaphthalene-1-sulfonic acid in the bacterial enzyme MurA
Reem K Fathalla, Matthias Engel, Christian Ducho
European Journal of Medicinal Chemistry
|
February 21, 2016
Systematic diversification of benzylidene heterocycles yields novel inhibitor scaffolds selective for Dyrk1A, Clk1 and CK2
Marica Mariano, Rolf W Hartmann, Matthias Engel
Medchemcomm
|
August 16, 2018
Design and synthesis of conformationally constraint Dyrk1A inhibitors by creating an intramolecular H-bond involving a benzothiazole core
Mohamed Salah, Mohammad Abdel-Halim, Matthias Engel
The Journal of Biological Chemistry
|
June 8, 2004
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines
Matthias Engel, Sybille Mazurek, Erich Eigenbrodt, et al.
Medchemcomm
|
August 16, 2018
Design and synthesis of novel 1,3,5-triphenyl pyrazolines as potential anti-inflammatory agents through allosteric inhibition of protein kinase Czeta (PKCζ)
Mohammad Abdel-Halim, Ashraf H Abadi, Matthias Engel
Analytical and Bioanalytical Chemistry
|
March 13, 2014
Screening Dyrk1A inhibitors by MALDI-QqQ mass spectrometry: systematic comparison to established radiometric, luminescence, and LC-UV-MS assays
David Gode, Christian Schmitt, Matthias Engel, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2014
Hydroxybenzothiophene Ketones Are Efficient Pre-mRNA Splicing Modulators Due to Dual Inhibition of Dyrk1A and Clk1/4
Christian Schmitt, Parisa Miralinaghi, Marica Mariano, et al.
Journal of Medicinal Chemistry
|
June 1, 2017
Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins
Ahmed K ElHady, Mohammad Abdel-Halim, Ashraf H Abadi, et al.
Chemmedchem
|
July 22, 2014
6-Hydroxybenzothiophene ketones: potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) owing to favorable molecule geometry and conformational preorganization
Parisa Miralinaghi, Christian Schmitt, Rolf W Hartmann, et al.
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Search research articles
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Showing results (1-10 of 79) with videos related to
Sort By:
Page
of 8
Bioorganic Chemistry
|
March 10, 2021
Synthesis, biological evaluation and molecular docking studies of indeno [1, 2-c] pyrazol derivatives as inhibitors of mitochondrial malate dehydrogenase 2 (MDH2)
Farzaneh Ahmadi, Matthias Engel, Mehdi M Baradarani
Archiv Der Pharmazie
|
July 19, 2023
Targeting the binding pocket of the fluorophore 8-anilinonaphthalene-1-sulfonic acid in the bacterial enzyme MurA
Reem K Fathalla, Matthias Engel, Christian Ducho
European Journal of Medicinal Chemistry
|
February 21, 2016
Systematic diversification of benzylidene heterocycles yields novel inhibitor scaffolds selective for Dyrk1A, Clk1 and CK2
Marica Mariano, Rolf W Hartmann, Matthias Engel
Medchemcomm
|
August 16, 2018
Design and synthesis of conformationally constraint Dyrk1A inhibitors by creating an intramolecular H-bond involving a benzothiazole core
Mohamed Salah, Mohammad Abdel-Halim, Matthias Engel
The Journal of Biological Chemistry
|
June 8, 2004
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines
Matthias Engel, Sybille Mazurek, Erich Eigenbrodt, et al.
Medchemcomm
|
August 16, 2018
Design and synthesis of novel 1,3,5-triphenyl pyrazolines as potential anti-inflammatory agents through allosteric inhibition of protein kinase Czeta (PKCζ)
Mohammad Abdel-Halim, Ashraf H Abadi, Matthias Engel
Analytical and Bioanalytical Chemistry
|
March 13, 2014
Screening Dyrk1A inhibitors by MALDI-QqQ mass spectrometry: systematic comparison to established radiometric, luminescence, and LC-UV-MS assays
David Gode, Christian Schmitt, Matthias Engel, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2014
Hydroxybenzothiophene Ketones Are Efficient Pre-mRNA Splicing Modulators Due to Dual Inhibition of Dyrk1A and Clk1/4
Christian Schmitt, Parisa Miralinaghi, Marica Mariano, et al.
Journal of Medicinal Chemistry
|
June 1, 2017
Development of Selective Clk1 and -4 Inhibitors for Cellular Depletion of Cancer-Relevant Proteins
Ahmed K ElHady, Mohammad Abdel-Halim, Ashraf H Abadi, et al.
Chemmedchem
|
July 22, 2014
6-Hydroxybenzothiophene ketones: potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) owing to favorable molecule geometry and conformational preorganization
Parisa Miralinaghi, Christian Schmitt, Rolf W Hartmann, et al.
Page
of 8