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European Journal of Medicinal Chemistry
|
October 28, 2021
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects
Yasmeen T AlNajjar, Moustafa Gabr, Ahmed K ElHady, et al.
Journal of Medicinal Chemistry
|
August 26, 2011
4-benzimidazolyl-3-phenylbutanoic acids as novel PIF-pocket-targeting allosteric inhibitors of protein kinase PKCζ
Wolfgang Fröhner, Laura A Lopez-Garcia, Sonja Neimanis, et al.
Journal of Medicinal Chemistry
|
January 29, 2019
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action
Benoît Bestgen, Irina Kufareva, Weiguang Seetoh, et al.
ACS Chemical Biology
|
August 6, 2013
PIF-pocket as a target for C. albicans Pkh selective inhibitors
Daniel Pastor-Flores, Jörg O Schulze, Anna Bahí, et al.
Journal of Medicinal Chemistry
|
October 31, 2012
2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept
Adriana Wilhelm, Laura A Lopez-Garcia, Katrien Busschots, et al.
Cancers
|
June 19, 2024
<i>N</i>-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, et al.
Pharmaceuticals (Basel, Switzerland)
|
July 27, 2022
Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors
Sarah S Darwish, Po-Jen Chen, Mostafa M Hamed, et al.
The Journal of Biological Chemistry
|
September 3, 2009
Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1)
Rosalia Dettori, Silvina Sonzogni, Lucas Meyer, et al.
The Journal of Biological Chemistry
|
July 13, 2024
Molecular insights into the regulatory landscape of PKC-related kinase-2 (PRK2/PKN2) using targeted small compounds
Lissy Z F Gross, Angelika F Winkel, Facundo Galceran, et al.
Bioorganic Chemistry
|
July 2, 2022
From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitors
Reem A Wagdy, Po-Jen Chen, Mostafa M Hamed, et al.
Page
of 8
Search research articles
Search
Showing results (41-50 of 79) with videos related to
Sort By:
Page
of 8
European Journal of Medicinal Chemistry
|
October 28, 2021
Discovery of novel 6-hydroxybenzothiazole urea derivatives as dual Dyrk1A/α-synuclein aggregation inhibitors with neuroprotective effects
Yasmeen T AlNajjar, Moustafa Gabr, Ahmed K ElHady, et al.
Journal of Medicinal Chemistry
|
August 26, 2011
4-benzimidazolyl-3-phenylbutanoic acids as novel PIF-pocket-targeting allosteric inhibitors of protein kinase PKCζ
Wolfgang Fröhner, Laura A Lopez-Garcia, Sonja Neimanis, et al.
Journal of Medicinal Chemistry
|
January 29, 2019
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action
Benoît Bestgen, Irina Kufareva, Weiguang Seetoh, et al.
ACS Chemical Biology
|
August 6, 2013
PIF-pocket as a target for C. albicans Pkh selective inhibitors
Daniel Pastor-Flores, Jörg O Schulze, Anna Bahí, et al.
Journal of Medicinal Chemistry
|
October 31, 2012
2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept
Adriana Wilhelm, Laura A Lopez-Garcia, Katrien Busschots, et al.
Cancers
|
June 19, 2024
<i>N</i>-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents
Noha Mostafa, Po-Jen Chen, Sarah S Darwish, et al.
Pharmaceuticals (Basel, Switzerland)
|
July 27, 2022
Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors
Sarah S Darwish, Po-Jen Chen, Mostafa M Hamed, et al.
The Journal of Biological Chemistry
|
September 3, 2009
Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1)
Rosalia Dettori, Silvina Sonzogni, Lucas Meyer, et al.
The Journal of Biological Chemistry
|
July 13, 2024
Molecular insights into the regulatory landscape of PKC-related kinase-2 (PRK2/PKN2) using targeted small compounds
Lissy Z F Gross, Angelika F Winkel, Facundo Galceran, et al.
Bioorganic Chemistry
|
July 2, 2022
From EGFR kinase inhibitors to anti-inflammatory drugs: Optimization and biological evaluation of (4-(phenylamino)quinazolinyl)-phenylthiourea derivatives as novel NF-κB inhibitors
Reem A Wagdy, Po-Jen Chen, Mostafa M Hamed, et al.
Page
of 8