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Bioorganic Chemistry
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November 4, 2020
Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors
Mohammad Abdel-Halim, Heather Tinsley, Adam B Keeton, et al.
Nature Chemical Biology
|
September 1, 2009
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1
Valerie Hindie, Adriana Stroba, Hua Zhang, et al.
Chemistry & Biology
|
September 25, 2012
Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site
Katrien Busschots, Laura A Lopez-Garcia, Carmen Lammi, et al.
ACS Pharmacology & Translational Science
|
June 19, 2025
Targeting Neutrophil-Mediated Inflammation: Identification of Pyrazolidinone Carboxamide Derivatives as Potent Selective Inhibitors of Formyl Peptide Receptor 1 (FPR1)-Activated Neutrophils
Mohammad Abdel-Halim, Reem A Wagdy, Mohamed Salah, et al.
Anti-Cancer Agents in Medicinal Chemistry
|
September 3, 2024
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription
Sara Sigler, Mohammad Abdel-Halim, Reem K Fathalla, et al.
Future Medicinal Chemistry
|
July 11, 2024
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, et al.
European Journal of Medicinal Chemistry
|
September 17, 2023
Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity
Reem A Wagdy, Nader S Abutaleb, Reem K Fathalla, et al.
Journal of Medicinal Chemistry
|
October 21, 2022
Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA
Reem K Fathalla, Wolfgang Fröhner, Chantal D Bader, et al.
Scientific Reports
|
November 6, 2019
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors
Irina Kufareva, Benoit Bestgen, Paul Brear, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry
|
September 19, 2024
Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways
Mohammad Abdel-Halim, Dalia S El-Gamil, Mennatallah A Hammam, et al.
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Search research articles
Search
Showing results (61-70 of 79) with videos related to
Sort By:
Page
of 8
Bioorganic Chemistry
|
November 4, 2020
Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors
Mohammad Abdel-Halim, Heather Tinsley, Adam B Keeton, et al.
Nature Chemical Biology
|
September 1, 2009
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1
Valerie Hindie, Adriana Stroba, Hua Zhang, et al.
Chemistry & Biology
|
September 25, 2012
Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site
Katrien Busschots, Laura A Lopez-Garcia, Carmen Lammi, et al.
ACS Pharmacology & Translational Science
|
June 19, 2025
Targeting Neutrophil-Mediated Inflammation: Identification of Pyrazolidinone Carboxamide Derivatives as Potent Selective Inhibitors of Formyl Peptide Receptor 1 (FPR1)-Activated Neutrophils
Mohammad Abdel-Halim, Reem A Wagdy, Mohamed Salah, et al.
Anti-Cancer Agents in Medicinal Chemistry
|
September 3, 2024
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription
Sara Sigler, Mohammad Abdel-Halim, Reem K Fathalla, et al.
Future Medicinal Chemistry
|
July 11, 2024
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity
Yara A Abd El-Rahman, Po-Jen Chen, Ahmed K ElHady, et al.
European Journal of Medicinal Chemistry
|
September 17, 2023
Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity
Reem A Wagdy, Nader S Abutaleb, Reem K Fathalla, et al.
Journal of Medicinal Chemistry
|
October 21, 2022
Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA
Reem K Fathalla, Wolfgang Fröhner, Chantal D Bader, et al.
Scientific Reports
|
November 6, 2019
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors
Irina Kufareva, Benoit Bestgen, Paul Brear, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry
|
September 19, 2024
Discovery of 1,3-disubstituted prop-2-en-1-one derivatives as inhibitors of neutrophilic inflammation via modulation of MAPK and Akt pathways
Mohammad Abdel-Halim, Dalia S El-Gamil, Mennatallah A Hammam, et al.
Page
of 8