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Nature Communications|April 28, 2022
Deficiency in coatomer complex I causes aberrant activation of STING signallingAnnemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, et al.
The Journal of Biological Chemistry|January 22, 2019
Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutationsMarina A Woeste, Sina Stern, Diana N Raju, et al.
Nature Communications|April 17, 2019
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylationMalgorzata Krajewska, Ruben Dries, Andrew V Grassetti, et al.
Nature Chemical Biology|August 30, 2016
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitorsTinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, et al.
The Journal of Experimental Medicine|October 31, 2022
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infectionLea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, et al.
Molecular Cell|April 1, 2019
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription ElongationApoorva Baluapuri, Julia Hofstetter, Nevenka Dudvarski Stankovic, et al.
The Journal of Allergy and Clinical Immunology|December 30, 2020
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severityJonas Moecking, Pawat Laohamonthonkul, Katelyn Chalker, et al.
Science Advances|September 12, 2020
CDK13 cooperates with CDK12 to control global RNA polymerase II processivityZheng Fan, Jennifer R Devlin, Simon J Hogg, et al.
European Journal of Human Genetics : EJHG|December 20, 2024
Role of ZFHX4 in orofacial clefting based on human genetic data and zebrafish modelsNina Ishorst, Selina Hölzel, Carola Greve, et al.
The EMBO Journal|December 20, 2024
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-IAlexander Kirchhoff, Anna-Maria Herzner, Christian Urban, et al.
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