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Journal of Computer-Aided Molecular Design
|
August 9, 2011
Computational investigation of the binding mode of bis(hydroxylphenyl)arenes in 17β-HSD1: molecular dynamics simulations, MM-PBSA free energy calculations, and molecular electrostatic potential maps
Matthias Negri, Maurizio Recanatini, Rolf W Hartmann
Plos One
|
August 14, 2010
Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation
Matthias Negri, Maurizio Recanatini, Rolf W Hartmann
Plos One
|
August 23, 2011
Structural basis for species specific inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1): computational study and biological validation
Tobias Klein, Claudia Henn, Matthias Negri, et al.
Chemmedchem
|
May 4, 2010
The role of fluorine substitution in biphenyl methylene imidazole-type CYP17 inhibitors for the treatment of prostate carcinoma
Qingzhong Hu, Matthias Negri, Sureyya Olgen, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 26, 2005
Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2)
Sarah Ulmschneider, Matthias Negri, Marieke Voets, et al.
Journal of Medicinal Chemistry
|
March 10, 2011
Fine-tuning the selectivity of aldosterone synthase inhibitors: structure-activity and structure-selectivity insights from studies of heteroaryl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one derivatives
Simon Lucas, Matthias Negri, Ralf Heim, et al.
Future Medicinal Chemistry
|
December 23, 2014
Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?
Elisabeth Weidel, Matthias Negri, Martin Empting, et al.
Plos One
|
January 14, 2012
Hydroxybenzothiazoles as new nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1)
Alessandro Spadaro, Matthias Negri, Sandrine Marchais-Oberwinkler, et al.
European Journal of Medicinal Chemistry
|
May 29, 2013
Novel small molecule inhibitors targeting the "switch region" of bacterial RNAP: structure-based optimization of a virtual screening hit
J Henning Sahner, Matthias Groh, Matthias Negri, et al.
Antimicrobial Agents and Chemotherapy
|
June 6, 2012
Influence of DNA template choice on transcription and inhibition of Escherichia coli RNA polymerase
Joerg Haupenthal, Kristina Hüsecken, Matthias Negri, et al.
Page
of 4
Search research articles
Search
Showing results (1-10 of 32) with videos related to
Sort By:
Page
of 4
Journal of Computer-Aided Molecular Design
|
August 9, 2011
Computational investigation of the binding mode of bis(hydroxylphenyl)arenes in 17β-HSD1: molecular dynamics simulations, MM-PBSA free energy calculations, and molecular electrostatic potential maps
Matthias Negri, Maurizio Recanatini, Rolf W Hartmann
Plos One
|
August 14, 2010
Insights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigation
Matthias Negri, Maurizio Recanatini, Rolf W Hartmann
Plos One
|
August 23, 2011
Structural basis for species specific inhibition of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1): computational study and biological validation
Tobias Klein, Claudia Henn, Matthias Negri, et al.
Chemmedchem
|
May 4, 2010
The role of fluorine substitution in biphenyl methylene imidazole-type CYP17 inhibitors for the treatment of prostate carcinoma
Qingzhong Hu, Matthias Negri, Sureyya Olgen, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 26, 2005
Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2)
Sarah Ulmschneider, Matthias Negri, Marieke Voets, et al.
Journal of Medicinal Chemistry
|
March 10, 2011
Fine-tuning the selectivity of aldosterone synthase inhibitors: structure-activity and structure-selectivity insights from studies of heteroaryl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one derivatives
Simon Lucas, Matthias Negri, Ralf Heim, et al.
Future Medicinal Chemistry
|
December 23, 2014
Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?
Elisabeth Weidel, Matthias Negri, Martin Empting, et al.
Plos One
|
January 14, 2012
Hydroxybenzothiazoles as new nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1)
Alessandro Spadaro, Matthias Negri, Sandrine Marchais-Oberwinkler, et al.
European Journal of Medicinal Chemistry
|
May 29, 2013
Novel small molecule inhibitors targeting the "switch region" of bacterial RNAP: structure-based optimization of a virtual screening hit
J Henning Sahner, Matthias Groh, Matthias Negri, et al.
Antimicrobial Agents and Chemotherapy
|
June 6, 2012
Influence of DNA template choice on transcription and inhibition of Escherichia coli RNA polymerase
Joerg Haupenthal, Kristina Hüsecken, Matthias Negri, et al.
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