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Journal of Medicinal Chemistry
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June 26, 2007
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors
Silvia Gobbi, Andrea Cavalli, Matthias Negri, et al.
Bioorganic & Medicinal Chemistry
|
August 5, 2008
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge
Qingzhong Hu, Matthias Negri, Kerstin Jahn-Hoffmann, et al.
Journal of Medicinal Chemistry
|
November 14, 2012
Structural optimization of 2,5-thiophene amides as highly potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors for the treatment of osteoporosis
Sandrine Marchais-Oberwinkler, Kuiying Xu, Marie Wetzel, et al.
Journal of Medicinal Chemistry
|
August 5, 2008
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivity
Ralf Heim, Simon Lucas, Cornelia M Grombein, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 21, 2007
Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17
Mariano A E Pinto-Bazurco Mendieta, Matthias Negri, Carsten Jagusch, et al.
Journal of Medicinal Chemistry
|
October 17, 2009
New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: influence of additional substituents on 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitory activity and selectivity
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Matthias Negri, et al.
Journal of Medicinal Chemistry
|
July 10, 2013
Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking
Elisabeth Weidel, Johannes C de Jong, Christian Brengel, et al.
Journal of Medicinal Chemistry
|
October 16, 2008
Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1)
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Ruth Werth, et al.
European Journal of Medicinal Chemistry
|
November 3, 2012
Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives
Nermin S Ahmed, Amal H Ali, Shreen M El-Nashar, et al.
The Journal of Steroid Biochemistry and Molecular Biology
|
January 4, 2011
17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development
Sandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 32) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
June 26, 2007
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors
Silvia Gobbi, Andrea Cavalli, Matthias Negri, et al.
Bioorganic & Medicinal Chemistry
|
August 5, 2008
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge
Qingzhong Hu, Matthias Negri, Kerstin Jahn-Hoffmann, et al.
Journal of Medicinal Chemistry
|
November 14, 2012
Structural optimization of 2,5-thiophene amides as highly potent and selective 17β-hydroxysteroid dehydrogenase type 2 inhibitors for the treatment of osteoporosis
Sandrine Marchais-Oberwinkler, Kuiying Xu, Marie Wetzel, et al.
Journal of Medicinal Chemistry
|
August 5, 2008
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivity
Ralf Heim, Simon Lucas, Cornelia M Grombein, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 21, 2007
Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17
Mariano A E Pinto-Bazurco Mendieta, Matthias Negri, Carsten Jagusch, et al.
Journal of Medicinal Chemistry
|
October 17, 2009
New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: influence of additional substituents on 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitory activity and selectivity
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Matthias Negri, et al.
Journal of Medicinal Chemistry
|
July 10, 2013
Structure optimization of 2-benzamidobenzoic acids as PqsD inhibitors for Pseudomonas aeruginosa infections and elucidation of binding mode by SPR, STD NMR, and molecular docking
Elisabeth Weidel, Johannes C de Jong, Christian Brengel, et al.
Journal of Medicinal Chemistry
|
October 16, 2008
Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1)
Emmanuel Bey, Sandrine Marchais-Oberwinkler, Ruth Werth, et al.
European Journal of Medicinal Chemistry
|
November 3, 2012
Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives
Nermin S Ahmed, Amal H Ali, Shreen M El-Nashar, et al.
The Journal of Steroid Biochemistry and Molecular Biology
|
January 4, 2011
17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development
Sandrine Marchais-Oberwinkler, Claudia Henn, Gabriele Möller, et al.
Page
of 4