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Matthias P Wymann

Showing results (41-50 of 80) with videos related to

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The Journal of Allergy and Clinical Immunology|May 21, 2013
Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergyEmilie Collmann, Thomas Bohnacker, Romina Marone, et al.
Neuropharmacology|August 7, 2018
The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsyClaudia Brandt, Petra Hillmann, Andreas Noack, et al.
The American Journal of Pathology|December 8, 2004
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitisEnrico Lupia, Alberto Goffi, Paolo De Giuli, et al.
The Journal of Experimental Medicine|February 28, 2007
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egressCésar Nombela-Arrieta, Thorsten R Mempel, Silvia F Soriano, et al.
Journal of the American Chemical Society|March 30, 2022
Covalent Proximity Scanning of a Distal Cysteine to Target PI3KαChiara Borsari, Erhan Keles, Jacob A McPhail, et al.
Blood|July 14, 2007
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammationHong Ji, Felix Rintelen, Caroline Waltzinger, et al.
European Journal of Immunology|March 2, 2005
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinasesMatthew J Thomas, Alexandra Smith, Denise H Head, et al.
Journal of Medicinal Chemistry|August 30, 2019
A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR InhibitorChiara Borsari, Denise Rageot, Alix Dall'Asen, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|October 9, 2024
Specific Requirement of the p84/p110γ Complex of PI3Kγ for Antibody-Activated, Inducible Cross-Presentation in Murine Type 2 DCsDespoina Koumantou, Aimé Cézaire Adiko, Pierre Bourdely, et al.
Journal of Medicinal Chemistry|October 26, 2018
Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological DisordersDenise Rageot, Thomas Bohnacker, Anna Melone, et al.
Pageof 8

Showing results (41-50 of 80) with videos related to

Sort By:
Pageof 8
The Journal of Allergy and Clinical Immunology|May 21, 2013
Transient targeting of phosphoinositide 3-kinase acts as a roadblock in mast cells' route to allergyEmilie Collmann, Thomas Bohnacker, Romina Marone, et al.
Neuropharmacology|August 7, 2018
The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsyClaudia Brandt, Petra Hillmann, Andreas Noack, et al.
The American Journal of Pathology|December 8, 2004
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitisEnrico Lupia, Alberto Goffi, Paolo De Giuli, et al.
The Journal of Experimental Medicine|February 28, 2007
A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egressCésar Nombela-Arrieta, Thorsten R Mempel, Silvia F Soriano, et al.
Journal of the American Chemical Society|March 30, 2022
Covalent Proximity Scanning of a Distal Cysteine to Target PI3KαChiara Borsari, Erhan Keles, Jacob A McPhail, et al.
Blood|July 14, 2007
Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammationHong Ji, Felix Rintelen, Caroline Waltzinger, et al.
European Journal of Immunology|March 2, 2005
Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinasesMatthew J Thomas, Alexandra Smith, Denise H Head, et al.
Journal of Medicinal Chemistry|August 30, 2019
A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR InhibitorChiara Borsari, Denise Rageot, Alix Dall'Asen, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|October 9, 2024
Specific Requirement of the p84/p110γ Complex of PI3Kγ for Antibody-Activated, Inducible Cross-Presentation in Murine Type 2 DCsDespoina Koumantou, Aimé Cézaire Adiko, Pierre Bourdely, et al.
Journal of Medicinal Chemistry|October 26, 2018
Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological DisordersDenise Rageot, Thomas Bohnacker, Anna Melone, et al.
Pageof 8