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Journal of Medicinal Chemistry
|
July 26, 2002
Selective alpha4beta7 integrin antagonists and their potential as antiinflammatory agents
Nathan J P Dubree, Dean R Artis, Georgette Castanedo, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 25, 2002
Solid-phase synthesis of dual alpha4beta1/alpha4beta7 integrin antagonists: two scaffolds with overlapping pharmacophores
Georgette M Castanedo, Fredrick C Sailes, Nathan J P Dubree, et al.
Nature Structural & Molecular Biology
|
August 22, 2017
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists
Yingnan Zhang, Mark Ultsch, Nicholas J Skelton, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells
Michael F T Koehler, Philippe Bergeron, Elizabeth M Blackwood, et al.
Cancer Research
|
August 19, 2017
Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer
Lingyan Jin, Jesse Garcia, Emily Chan, et al.
Nature Communications
|
December 11, 2025
Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera
Jin Du, Elisia Villemure, Matthew Johnson, et al.
Nature Communications
|
December 15, 2020
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 25, 2017
Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300
Kwong Wah Lai, F Anthony Romero, Vickie Tsui, et al.
Journal of Medicinal Chemistry
|
May 15, 2024
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, et al.
Journal of Medicinal Chemistry
|
November 21, 2017
A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors
Sarah M Bronner, Jeremy Murray, F Anthony Romero, et al.
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Search research articles
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Showing results (11-20 of 28) with videos related to
Sort By:
Page
of 3
Journal of Medicinal Chemistry
|
July 26, 2002
Selective alpha4beta7 integrin antagonists and their potential as antiinflammatory agents
Nathan J P Dubree, Dean R Artis, Georgette Castanedo, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 25, 2002
Solid-phase synthesis of dual alpha4beta1/alpha4beta7 integrin antagonists: two scaffolds with overlapping pharmacophores
Georgette M Castanedo, Fredrick C Sailes, Nathan J P Dubree, et al.
Nature Structural & Molecular Biology
|
August 22, 2017
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists
Yingnan Zhang, Mark Ultsch, Nicholas J Skelton, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells
Michael F T Koehler, Philippe Bergeron, Elizabeth M Blackwood, et al.
Cancer Research
|
August 19, 2017
Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer
Lingyan Jin, Jesse Garcia, Emily Chan, et al.
Nature Communications
|
December 11, 2025
Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera
Jin Du, Elisia Villemure, Matthew Johnson, et al.
Nature Communications
|
December 15, 2020
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 25, 2017
Design and synthesis of a biaryl series as inhibitors for the bromodomains of CBP/P300
Kwong Wah Lai, F Anthony Romero, Vickie Tsui, et al.
Journal of Medicinal Chemistry
|
May 15, 2024
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, et al.
Journal of Medicinal Chemistry
|
November 21, 2017
A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors
Sarah M Bronner, Jeremy Murray, F Anthony Romero, et al.
Page
of 3