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Current Opinion in Microbiology|July 13, 2020
The bidirectional nature of microbiome-epithelial cell interactionsAngel G Solis, Max Klapholz, Jingru Zhao, et al.The Journal of Pathology|February 4, 2022
Presence of Tim3+ and PD-1+ CD8+ T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and distinct clinicopathological featuresMax Klapholz, Michael G Drage, Amitabh Srivastava, et al.Immunity|January 13, 2019
Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T CellsSema Kurtulus, Asaf Madi, Giulia Escobar, et al.Molecular Pharmacology|August 9, 2020
Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize DrugsZdenek Dvorak, Max Klapholz, Thomas P Burris, et al.Immunity|April 13, 2022
The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockadeLisa Cucolo, Qingzhou Chen, Jingya Qiu, et al.Immunity|September 16, 2020
Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor MicroenvironmentNandini Acharya, Asaf Madi, Huiyuan Zhang, et al.Oncoimmunology|January 9, 2018
Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacyCatherine A Sabatos-Peyton, James Nevin, Ansgar Brock, et al.Biorxiv : the Preprint Server for Biology|June 4, 2026
PD-1 blockade drug holiday improves exhausted progenitor CD8 T cell (Tpex) reinvigoration by avoiding Tpex adaptive resistanceShin Foong Ngiow, Ryan P O'Connell, Sasikanth Manne, et al.Immunity|June 14, 2023
The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cellsAmy E Baxter, Hua Huang, Josephine R Giles, et al.Immunity|December 13, 2023
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposureJean-Christophe Beltra, Mohamed S Abdel-Hakeem, Sasikanth Manne, et al.Pageof 2