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Proceedings of the National Academy of Sciences of the United States of America
|
December 8, 2009
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
Dirk Roymans, Hendrik L De Bondt, Eric Arnoult, et al.
Journal of Medicinal Chemistry
|
January 23, 2014
Discovery and development of simeprevir (TMC435), a HCV NS3/4A protease inhibitor
Åsa Rosenquist, Bertil Samuelsson, Per-Ola Johansson, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 25, 2005
1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2-p53 interaction: discovery and SAR
Daniel J Parks, Louis V Lafrance, Raul R Calvo, et al.
Journal of Medicinal Chemistry
|
June 11, 2009
Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase
Koen Vandyck, Maxwell D Cummings, Origène Nyanguile, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2020
Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach
Christoph Steeneck, Christian Gege, Olaf Kinzel, et al.
Angewandte Chemie (International Ed. in English)
|
February 19, 2010
Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target
Maxwell D Cummings, Jimmy Lindberg, Tse-I Lin, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2018
Identification and biological evaluation of thiazole-based inverse agonists of RORγt
Christian Gege, Maxwell D Cummings, Michael Albers, et al.
Antimicrobial Agents and Chemotherapy
|
October 15, 2008
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors
Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 8, 2006
A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s
Nalin L Subasinghe, Jeremy M Travins, Farah Ali, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 28, 2020
Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt
Christian Gege, Michael Albers, Olaf Kinzel, et al.
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of 6
Search research articles
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Showing results (21-30 of 52) with videos related to
Sort By:
Page
of 6
Proceedings of the National Academy of Sciences of the United States of America
|
December 8, 2009
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
Dirk Roymans, Hendrik L De Bondt, Eric Arnoult, et al.
Journal of Medicinal Chemistry
|
January 23, 2014
Discovery and development of simeprevir (TMC435), a HCV NS3/4A protease inhibitor
Åsa Rosenquist, Bertil Samuelsson, Per-Ola Johansson, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 25, 2005
1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2-p53 interaction: discovery and SAR
Daniel J Parks, Louis V Lafrance, Raul R Calvo, et al.
Journal of Medicinal Chemistry
|
June 11, 2009
Structure-based design of a benzodiazepine scaffold yields a potent allosteric inhibitor of hepatitis C NS5B RNA polymerase
Koen Vandyck, Maxwell D Cummings, Origène Nyanguile, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2020
Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach
Christoph Steeneck, Christian Gege, Olaf Kinzel, et al.
Angewandte Chemie (International Ed. in English)
|
February 19, 2010
Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target
Maxwell D Cummings, Jimmy Lindberg, Tse-I Lin, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2018
Identification and biological evaluation of thiazole-based inverse agonists of RORγt
Christian Gege, Maxwell D Cummings, Michael Albers, et al.
Antimicrobial Agents and Chemotherapy
|
October 15, 2008
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors
Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 8, 2006
A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s
Nalin L Subasinghe, Jeremy M Travins, Farah Ali, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 28, 2020
Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt
Christian Gege, Michael Albers, Olaf Kinzel, et al.
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of 6