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Angewandte Chemie (International Ed. in English)
|
April 5, 2012
Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties
Maxwell D Cummings, Tse-I Lin, Lili Hu, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 29, 2017
6-Substituted quinolines as RORγt inverse agonists
J Kent Barbay, Maxwell D Cummings, Marta Abad, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 1, 2012
Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series
David McGowan, Sandrine Vendeville, Tse-I Lin, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2008
Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s
Jeremy M Travins, Farah Ali, Hui Huang, et al.
Journal of Virology
|
January 15, 2010
1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus
Origène Nyanguile, Benoit Devogelaere, Leen Vijgen, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 29, 2012
Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055
Sandrine Vendeville, Tse-I Lin, Lili Hu, et al.
Molecular Cancer Therapeutics
|
January 25, 2006
Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
Holly K Koblish, Shuyuan Zhao, Carol F Franks, et al.
Journal of Medicinal Chemistry
|
November 2, 2010
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase
Tim H M Jonckers, Tse-I Lin, Christophe Buyck, et al.
The Journal of Biological Chemistry
|
January 7, 2005
Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology
Theodore E Carver, Brian Bordeau, Maxwell D Cummings, et al.
Journal of Medicinal Chemistry
|
February 18, 2005
Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells
Bruce L Grasberger, Tianbao Lu, Carsten Schubert, et al.
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Search research articles
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Showing results (41-50 of 52) with videos related to
Sort By:
Page
of 6
Angewandte Chemie (International Ed. in English)
|
April 5, 2012
Structure-based macrocyclization yields hepatitis C virus NS5B inhibitors with improved binding affinities and pharmacokinetic properties
Maxwell D Cummings, Tse-I Lin, Lili Hu, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 29, 2017
6-Substituted quinolines as RORγt inverse agonists
J Kent Barbay, Maxwell D Cummings, Marta Abad, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 1, 2012
Finger-loop inhibitors of the HCV NS5b polymerase. Part 1: Discovery and optimization of novel 1,6- and 2,6-macrocyclic indole series
David McGowan, Sandrine Vendeville, Tse-I Lin, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 5, 2008
Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s
Jeremy M Travins, Farah Ali, Hui Huang, et al.
Journal of Virology
|
January 15, 2010
1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus
Origène Nyanguile, Benoit Devogelaere, Leen Vijgen, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 29, 2012
Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055
Sandrine Vendeville, Tse-I Lin, Lili Hu, et al.
Molecular Cancer Therapeutics
|
January 25, 2006
Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
Holly K Koblish, Shuyuan Zhao, Carol F Franks, et al.
Journal of Medicinal Chemistry
|
November 2, 2010
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase
Tim H M Jonckers, Tse-I Lin, Christophe Buyck, et al.
The Journal of Biological Chemistry
|
January 7, 2005
Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology
Theodore E Carver, Brian Bordeau, Maxwell D Cummings, et al.
Journal of Medicinal Chemistry
|
February 18, 2005
Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells
Bruce L Grasberger, Tianbao Lu, Carsten Schubert, et al.
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of 6