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Cancer Discovery|December 18, 2012
The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescenceMeaghan Wall, Gretchen Poortinga, Kym L Stanley, et al.
Science Signaling|September 1, 2011
AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancerJoanna C Chan, Katherine M Hannan, Kim Riddell, et al.
European Journal of Cancer (Oxford, England : 1990)|September 10, 2013
Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitorsKaren E Sheppard, Carleen Cullinane, Katherine M Hannan, et al.
Blood|October 12, 2022
Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changesMonika I Linder, Yoko Mizoguchi, Sebastian Hesse, et al.
Cancer Cell|July 14, 2012
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53Megan J Bywater, Gretchen Poortinga, Elaine Sanij, et al.
European Journal of Human Genetics : EJHG|November 29, 2022
Comparing saliva and blood for the detection of mosaic genomic abnormalities that cause syndromic intellectual disabilityDavid I Francis, Zornitza Stark, Ingrid E Scheffer, et al.
Science Translational Medicine|February 26, 2025
Single-cell analysis of aplastic anemia reveals a convergence of NK and NK-like CD8+ T cells with a disease-associated TCR signatureSofie Lundgren, Jani Huuhtanen, Mikko Keränen, et al.
BMJ Open|April 3, 2024
Prospective cohort study of genomic newborn screening: BabyScreen+ pilot study protocolSebastian Lunke, Sophie E Bouffler, Lilian Downie, et al.
Science Translational Medicine|May 14, 2025
Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac diseaseMandeep Singh, Raymond H Y Louie, Jerome Samir, et al.
Blood|February 22, 2022
Enhancer retargeting of CDX2 and UBTF::ATXN7L3 define a subtype of high-risk B-progenitor acute lymphoblastic leukemiaShunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, et al.
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