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American Journal of Cancer Research|March 21, 2020
Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancerYu-Yi Chu, Clinton Yam, Mei-Kuang Chen, et al.Cancer Discovery|March 29, 2024
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient CancersGuang Lei, Chao Mao, Amber D Horbath, et al.Cancer Research|June 28, 2014
Definition of PKC-α, CDK6, and MET as therapeutic targets in triple-negative breast cancerYi-Hsin Hsu, Jun Yao, Li-Chuan Chan, et al.Nature Communications|December 13, 2019
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell deathJerry H Houl, Zu Ye, Chris A Brosey, et al.Nature Cancer|October 17, 2022
Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complexYu-Yi Chu, Mei-Kuang Chen, Yongkun Wei, et al.Nature Medicine|January 19, 2016
Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitorsYi Du, Hirohito Yamaguchi, Yongkun Wei, et al.American Journal of Cancer Research|May 11, 2023
Nuclear export signal mutation of epidermal growth factor receptor enhances malignant phenotypes of cancer cellsLei Nie, Ying-Nai Wang, Jung-Mao Hsu, et al.The Journal of Clinical Investigation|June 3, 2025
FGFR3-induced Y158 PARP1 phosphorylation promotes PARP inhibitor resistance via BRG1/MRE11-mediated DNA repair in breast cancer modelsMei-Kuang Chen, Hirohito Yamaguchi, Yuan Gao, et al.Pageof 5