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Meihua Tu

Showing results (11-20 of 41) with videos related to

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Protein Expression and Purification|January 27, 2015
Expression and functional characterization of human lysosomal acid lipase gene (LIPA) mutation responsible for cholesteryl ester storage disease (CESD) phenotypeFrancis Rajamohan, Allan R Reyes, Wanida Ruangsiriluk, et al.
Current Topics in Medicinal Chemistry|April 13, 2013
Medicinal chemistry design principles for liver targeting through OATP transportersMeihua Tu, Alan M Mathiowetz, Jeffrey A Pfefferkorn, et al.
Journal of Lipid Research|June 3, 2020
Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage diseaseFrancis Rajamohan, Allan R Reyes, Meihua Tu, et al.
Nature Structural & Molecular Biology|July 14, 2022
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphateThomas J McCorvie, Paula M Loria, Meihua Tu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2014
Toward a unified model of passive drug permeation II: the physiochemical determinants of unbound tissue distribution with applications to the design of hepatoselective glucokinase activatorsAvijit Ghosh, Tristan S Maurer, John Litchfield, et al.
Journal of Lipid Research|October 11, 2008
The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and bindingOmar L Francone, Meihua Tu, Lori J Royer, et al.
The Journal of Biological Chemistry|September 29, 2011
Structure-guided inhibitor design for human acetyl-coenzyme A carboxylase by interspecies active site conversionFrancis Rajamohan, Eric Marr, Allan R Reyes, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2010
Intrinsic electrophilicity of the 4-methylsulfonyl-2-pyridone scaffold in glucokinase activators: role of glutathione-S-transferases and in vivo quantitation of a glutathione conjugate in ratsJohn Litchfield, Raman Sharma, Karen Atkinson, et al.
Journal of Chemical Information and Modeling|April 11, 2012
Exploring aromatic chemical space with NEAT: novel and electronically equivalent aromatic templateMeihua Tu, Brajesh K Rai, Alan M Mathiowetz, et al.
Journal of Medicinal Chemistry|January 19, 2007
Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitorsThomas A Chappie, John M Humphrey, Martin P Allen, et al.
Pageof 5

Showing results (11-20 of 41) with videos related to

Sort By:
Pageof 5
Protein Expression and Purification|January 27, 2015
Expression and functional characterization of human lysosomal acid lipase gene (LIPA) mutation responsible for cholesteryl ester storage disease (CESD) phenotypeFrancis Rajamohan, Allan R Reyes, Wanida Ruangsiriluk, et al.
Current Topics in Medicinal Chemistry|April 13, 2013
Medicinal chemistry design principles for liver targeting through OATP transportersMeihua Tu, Alan M Mathiowetz, Jeffrey A Pfefferkorn, et al.
Journal of Lipid Research|June 3, 2020
Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage diseaseFrancis Rajamohan, Allan R Reyes, Meihua Tu, et al.
Nature Structural & Molecular Biology|July 14, 2022
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphateThomas J McCorvie, Paula M Loria, Meihua Tu, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2014
Toward a unified model of passive drug permeation II: the physiochemical determinants of unbound tissue distribution with applications to the design of hepatoselective glucokinase activatorsAvijit Ghosh, Tristan S Maurer, John Litchfield, et al.
Journal of Lipid Research|October 11, 2008
The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and bindingOmar L Francone, Meihua Tu, Lori J Royer, et al.
The Journal of Biological Chemistry|September 29, 2011
Structure-guided inhibitor design for human acetyl-coenzyme A carboxylase by interspecies active site conversionFrancis Rajamohan, Eric Marr, Allan R Reyes, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2010
Intrinsic electrophilicity of the 4-methylsulfonyl-2-pyridone scaffold in glucokinase activators: role of glutathione-S-transferases and in vivo quantitation of a glutathione conjugate in ratsJohn Litchfield, Raman Sharma, Karen Atkinson, et al.
Journal of Chemical Information and Modeling|April 11, 2012
Exploring aromatic chemical space with NEAT: novel and electronically equivalent aromatic templateMeihua Tu, Brajesh K Rai, Alan M Mathiowetz, et al.
Journal of Medicinal Chemistry|January 19, 2007
Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitorsThomas A Chappie, John M Humphrey, Martin P Allen, et al.
Pageof 5