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Cancers|September 10, 2021
Insights from IgE Immune Surveillance in Allergy and Cancer for Anti-Tumour IgE TreatmentsAlex J McCraw, Jitesh Chauhan, Heather J Bax, et al.Journal of Experimental & Clinical Cancer Research : CR|February 11, 2025
An IgE antibody targeting HER2 identified by clonal selection restricts breast cancer growth via immune-stimulating activitiesLais C G F Palhares, Melanie Grandits, Katie Stoker, et al.Mabs|July 14, 2025
Tuning antibody stability and function by rational designs of framework mutationsJoseph C F Ng, Alicia Chenoweth, Maria Laura De Sciscio, et al.Breast Cancer Research : BCR|May 5, 2023
Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitorsVera E van der Noord, Wanda van der Stel, Gijs Louwerens, et al.Journal for Immunotherapy of Cancer|March 12, 2025
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumorsMelanie Grandits, Lais C G F Palhares, Gabriel Osborn, et al.Mabs|January 20, 2025
Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice productionHeather J Bax, Jitesh Chauhan, Alexandra J McCraw, et al.Chemico-Biological Interactions|October 31, 2021
The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compoundsTim Brecklinghaus, Wiebke Albrecht, Franziska Kappenberg, et al.Journal for Immunotherapy of Cancer|June 11, 2021
Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2Giulia Pellizzari, Olivier Martinez, Silvia Crescioli, et al.Nature Communications|April 10, 2025
Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interactionGabriel Osborn, Jacobo López-Abente, Rebecca Adams, et al.NPJ Precision Oncology|March 7, 2026
An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancerBenjamina Esapa, Yi Liu, Alicia M Chenoweth, et al.Pageof 4