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The Journal of Biological Chemistry|October 6, 2019
Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretionNicola M Blythe, Katsuhiko Muraki, Melanie J Ludlow, et al.
British Journal of Pharmacology|December 2, 2022
Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1Gregory Parsonage, Kevin Cuthbertson, Naima Endesh, et al.
Communications Biology|April 3, 2023
PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensingEulashini Chuntharpursat-Bon, Oleksandr V Povstyan, Melanie J Ludlow, et al.
The Journal of Biological Chemistry|March 23, 2017
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channelsHussein N Rubaiy, Melanie J Ludlow, Matthias Henrot, et al.
British Journal of Pharmacology|November 14, 2015
Natural and synthetic flavonoid modulation of TRPC5 channelsJacqueline Naylor, Aisling Minard, Hannah J Gaunt, et al.
Iscience|August 12, 2025
PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescueMelanie J Ludlow, Oleksandr V Povstyan, Deborah M Linley, et al.
Nature Communications|August 26, 2017
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performanceBaptiste Rode, Jian Shi, Naima Endesh, et al.
Nature|August 15, 2014
Piezo1 integration of vascular architecture with physiological forceJing Li, Bing Hou, Sarka Tumova, et al.
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