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Biochemistry|February 11, 2025
Distinct Acyl Carrier Protein Docking Sites Help Mediate the Opposite Stereoselectivities of A- and B-type Modular Polyketide Synthase KetoreductasesKatherine A Ray, Sally N Lin, Adrian T Keatinge-Clay
Chemical Communications (Cambridge, England)|November 17, 2015
Substrate structure-activity relationships guide rational engineering of modular polyketide synthase ketoreductasesConstance B Bailey, Marjolein E Pasman, Adrian T Keatinge-Clay
Biochemistry|January 31, 2012
Structural studies of the spinosyn rhamnosyltransferase, SpnGEta A Isiorho, Hung-wen Liu, Adrian T Keatinge-Clay
ACS Chemical Biology|August 5, 2014
A double-hotdog with a new trick: structure and mechanism of the trans-acyltransferase polyketide synthase enoyl-isomeraseDarren C Gay, Philip J Spear, Adrian T Keatinge-Clay
Metabolic Engineering|May 31, 2023
Boosting titers of engineered triketide and tetraketide synthases to record levels through T7 promoter tuningJie Zhang, Ramesh Bista, Takeshi Miyazawa, et al.
Research Square|August 7, 2023
Assessing and harnessing updated polyketide synthase modules through combinatorial engineeringKatherine A Ray, Joshua D Lutgens, Ramesh Bista, et al.
Nature Communications|August 1, 2024
Assessing and harnessing updated polyketide synthase modules through combinatorial engineeringKatherine A Ray, Joshua D Lutgens, Ramesh Bista, et al.
Research Square|April 8, 2025
A CRISPR-Cas9 System for Knock-out and Knock-in of High Molecular Weight DNA Enables Module-Swapping of the Pikromycin Synthase in its Native HostZhe-Chong Wang, Hayden Stegall, Takeshi Miyazawa, et al.
Biochemistry|April 4, 2015
Molecular dynamics studies of modular polyketide synthase ketoreductase stereospecificityMauro L Mugnai, Yue Shi, Adrian T Keatinge-Clay, et al.
Structure (London, England : 1993)|August 11, 2010
Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthaseJianting Zheng, Clint A Taylor, Shawn K Piasecki, et al.
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