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Analytical Chemistry|April 29, 2011
Detection of trace proteins in multicomponent mixtures using displacement chromatographySteven T Evans, Melissa Holstein, Steven M Cramer
Biotechnology Progress|October 20, 2022
Use of Monte Carlo simulations for improved facility fit planning in downstream biomanufacturing and technology transferChristopher Furcht, Michael VanSeveren, Melissa Holstein, et al.
Biotechnology and Bioengineering|January 13, 2022
Assessing detergent-mediated virus inactivation, protein stability, and impurity clearance in biologics downstream processesHasin Feroz, Naresh Chennamsetty, Sara Byers, et al.
Biotechnology Journal|April 26, 2025
Impact of Eco-Friendly Surfactant Structure and Class on Enveloped Virus InactivationVaishali Sharma, Lynn Manchester, Melissa Holstein, et al.
Biotechnology Progress|January 19, 2026
A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measuresSolomon Isu, Derek Silva, Melissa Holstein, et al.
Biotechnology Journal|May 26, 2018
Continuous In-Line Virus Inactivation for Next Generation BioprocessingChristopher Gillespie, Melissa Holstein, Lori Mullin, et al.
Journal of Pharmaceutical Sciences|April 14, 2024
Understanding the Impact of Combined Hydrodynamic Shear and Interfacial Dilatational Stress, on Interface-Mediated Particle Formation for Monoclonal Antibody FormulationsValerie P Griffin, Samantha Pace, Maria Olu Ogunyankin, et al.
Biotechnology Journal|August 29, 2023
The role of intermolecular interactions on monoclonal antibody filtration through virus removal membranesMatthew Billups, Mirko Minervini, Melissa Holstein, et al.
Journal of Chromatography. A|September 8, 2009
Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein libraryWai Keen Chung, Ying Hou, Melissa Holstein, et al.
Biotechnology Journal|September 10, 2021
Surrogate model to screen for inactivation-based clearance of enveloped viruses during biotherapeutics process developmentHasin Feroz, Daniel Cetnar, Robert Hewlett, et al.
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