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Scientific Reports|May 25, 2016
An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitisMeng-Chen Lu, Jian-Ai Ji, Yong-Lin Jiang, et al.Journal of Computer-Aided Molecular Design|October 11, 2014
Investigation of the intermolecular recognition mechanism between the E3 ubiquitin ligase Keap1 and substrate based on multiple substrates analysisZheng-Yu Jiang, Li-Li Xu, Meng-Chen Lu, et al.Current Drug Targets|August 6, 2014
Insights into targeting NEMO for pharmacological regulationHong-Xi Chu, Jun-Feng Zhu, Jing-Jie Huang, et al.Journal of Medicinal Chemistry|February 12, 2014
Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysisZheng-Yu Jiang, Meng-Chen Lu, Li Li Xu, et al.Journal of Medicinal Chemistry|August 11, 2015
Structure-Activity and Structure-Property Relationship and Exploratory in Vivo Evaluation of the Nanomolar Keap1-Nrf2 Protein-Protein Interaction InhibitorZheng-Yu Jiang, Li Li Xu, Meng-Chen Lu, et al.Scientific Reports|January 9, 2016
CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cellsXiao-Li Xu, Qi-chao Bao, Jian-Min Jia, et al.Journal of Chemical Information and Modeling|September 21, 2013
Effective screening strategy using ensembled pharmacophore models combined with cascade docking: application to p53-MDM2 interaction inhibitorsXin Xue, Jin-Lian Wei, Li-Li Xu, et al.Journal of Medicinal Chemistry|June 26, 2015
Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship StudyLi-Li Xu, Jun-Feng Zhu, Xiao-Li Xu, et al.Pageof 2