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Molecular Cell|May 13, 2026
High-throughput screening approach identifies substrate-selective Hsp104 variants that counter amyloid seeding with diminished off-target effectsJeremy J Ryan, Karlie R Miller, Anuradhika Puri, et al.Elife|December 15, 2020
Therapeutic genetic variation revealed in diverse Hsp104 homologsZachary M March, Katelyn Sweeney, Hanna Kim, et al.Biorxiv : the Preprint Server for Biology|January 30, 2023
MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathyYeawon Kim, Chuang Li, Chenjian Gu, et al.Nature Communications|October 14, 2023
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in miceYeawon Kim, Chuang Li, Chenjian Gu, et al.Cell Reports|August 22, 2019
Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein ProteotoxicityAmber Tariq, JiaBei Lin, Meredith E Jackrel, et al.Cell|April 21, 2018
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like DomainsLin Guo, Hong Joo Kim, Hejia Wang, et al.Pageof 5