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Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|September 2, 2020
Modulation of arousal and sleep/wake architecture by M1 PAM VU0453595 across young and aged rodents and nonhuman primatesRobert W Gould, Jason K Russell, Michael T Nedelcovych, et al.
ACS Chemical Neuroscience|July 4, 2019
Acute Negative Allosteric Modulation of M5 Muscarinic Acetylcholine Receptors Inhibits Oxycodone Self-Administration and Cue-Induced Reactivity with No Effect on AntinociceptionRobert W Gould, Barak W Gunter, Michael Bubser, et al.
ACS Chemical Neuroscience|November 27, 2018
Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain ModelsKristopher K Abney, Michael Bubser, Yu Du, et al.
Research Square|April 16, 2025
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of the Muscarinic M 1 Positive Allosteric Modulator VU0467319 for Alzheimer's disease: A Single Ascending-Dose Study in Healthy ParticipantsAlexander C Conley, Alexandra P Key, Jennifer U Blackford, et al.
Alzheimer'S Research & Therapy|July 2, 2025
Safety, tolerability, pharmacokinetic and pharmacodynamic effects of the muscarinic M1 positive allosteric modulator VU0467319 for Alzheimer's disease: a single ascending-dose study in healthy participantsAlexander C Conley, Alexandra P Key, Jennifer U Blackford, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 17, 2017
OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behaviorIsaac D Zike, Muhammad O Chohan, Jared M Kopelman, et al.
Neuropharmacology|July 22, 2017
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M4 PAM VU0467154Robert W Gould, Michael D Grannan, Barak W Gunter, et al.
ACS Chemical Biology|August 20, 2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenicsHyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, et al.
ACS Chemical Neuroscience|July 22, 2016
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 HeteromersColleen M Niswender, Carrie K Jones, Xin Lin, et al.
Molecular Psychiatry|August 18, 2018
Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulatorsSamantha E Yohn, Daniel J Foster, Dan P Covey, et al.
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