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Journal of Medicinal Chemistry|July 5, 2022
SAGE-718: A First-in-Class <i>N</i>-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive ImpairmentMatthew D Hill, Maria-Jesus Blanco, Francesco G Salituro, et al.Journal of Medicinal Chemistry|August 8, 2019
Neuroactive Steroid <i>N</i>-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological ActivityDaniel S La, Francesco G Salituro, Gabriel Martinez Botella, et al.Journal of Neurophysiology|September 26, 2014
EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic dosesEdward P Christian, Dean H Snyder, Wei Song, et al.Neuropharmacology|September 25, 2020
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABA<sub>A</sub> receptor positive allosteric modulatorAlison L Althaus, Michael A Ackley, Gabriel M Belfort, et al.Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|September 30, 2016
Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled StudyGerard Sanacora, Michael R Johnson, Arif Khan, et al.Biochemical Pharmacology|July 21, 2009
Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processesSimon Sydserff, E J Sutton, Dekun Song, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 13, 2009
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learningJana K Shirey, Ashley E Brady, Paulianda J Jones, et al.Biological Psychiatry|April 17, 2026
Baseline Mismatch Negativity Amplitude Predicts Direction and Magnitude of Ketamine Effect in Healthy Volunteers - A "Disordinal" EffectMarco Cecchi, Jason Johannesen, Brandon Farley, et al.Pageof 2