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Nature Communications|September 28, 2022
Activation of the human insulin receptor by non-insulin-related peptidesNicholas S Kirk, Qi Chen, Yingzhe Ginger Wu, et al.Journal of Molecular Biology|October 20, 2009
Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational changeAndrew E Whitten, Brian J Smith, John G Menting, et al.Proceedings of the National Academy of Sciences of the United States of America|March 30, 2010
Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonistsBrian J Smith, Kun Huang, Geoffrey Kong, et al.The Journal of Biological Chemistry|November 9, 2017
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native proteinMichael D Glidden, Khadijah Aldabbagh, Nelson B Phillips, et al.Nature Structural & Molecular Biology|September 13, 2016
A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulinJohn G Menting, Joanna Gajewiak, Christopher A MacRaild, et al.Nature|January 11, 2013
How insulin engages its primary binding site on the insulin receptorJohn G Menting, Jonathan Whittaker, Mai B Margetts, et al.Nature Structural & Molecular Biology|June 14, 2020
Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principlesXiaochun Xiong, John G Menting, Maria M Disotuar, et al.Nature Structural & Molecular Biology|June 3, 2020
A structurally minimized yet fully active insulin based on cone-snail venom insulin principlesXiaochun Xiong, John G Menting, Maria M Disotuar, et al.Nature Chemical Biology|March 15, 2022
Symmetric and asymmetric receptor conformation continuum induced by a new insulinXiaochun Xiong, Alan Blakely, Jin Hwan Kim, et al.Proceedings of the National Academy of Sciences of the United States of America|August 6, 2014
Protective hinge in insulin opens to enable its receptor engagementJohn G Menting, Yanwu Yang, Shu Jin Chan, et al.Pageof 10