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The Journal of Biological Chemistry|November 5, 2013
Development of functionally selective, small molecule agonists at kappa opioid receptorsLei Zhou, Kimberly M Lovell, Kevin J Frankowski, et al.Nature|March 31, 2012
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonistsLaura A Solt, Yongjun Wang, Subhashis Banerjee, et al.Neuropharmacology|June 21, 2021
A promising chemical series of positive allosteric modulators of the μ-opioid receptor that enhance the antinociceptive efficacy of opioids but not their adverse effectsKerri D Pryce, Hye Jin Kang, Farhana Sakloth, et al.Science Signaling|December 1, 2016
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoriaTarsis F Brust, Jenny Morgenweck, Susy A Kim, et al.Proceedings of the National Academy of Sciences of the United States of America|October 27, 2017
M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memoryClaude-Henry Volmar, Hasib Salah-Uddin, Karolina J Janczura, et al.Biorxiv : the Preprint Server for Biology|May 15, 2024
MT-125 Inhibits Non-Muscle Myosin IIA and IIB, Synergizes with Oncogenic Kinase Inhibitors, and Prolongs Survival in GlioblastomaRajappa Kenchappa, Laszlo Radnai, Erica J Young, et al.ACS Medicinal Chemistry Letters|September 24, 2015
Design, Synthesis, and Biological Evaluation of Indole Biphenylcarboxylic Acids as PPARγ AntagonistsAlice Asteian, Anne-Laure Blayo, Yuanjun He, et al.Cell Reports. Medicine|November 27, 2025
A triple-action PROTAC for wild-type p53 cancer therapyGregory H Bird, Utsarga Adhikary, Michael J Schmidt, et al.Cell Reports|August 24, 2025
Exogenous estrogen enhances T cell activation in male primatesPatricia A Hahn, Joan Escrivà-Font, Eric S Alexander, et al.Journal of Medicinal Chemistry|March 14, 2018
Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial RespirationHua Lin, Jonathan Z Long, Alexander M Roche, et al.Pageof 15