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Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|April 30, 2026
Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine TransferBeau R Brummel, Sofia Kokkaliari, Qiwen Gao, et al.Plos Biology|June 12, 2018
Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activationJing Zhao, Lei Zhang, Xiaodong Mu, et al.ACS Chemical Biology|September 24, 2015
Selective Targeting of Extracellular Insulin-Degrading Enzyme by Quasi-Irreversible Thiol-Modifying InhibitorsSamer O Abdul-Hay, Thomas D Bannister, Hui Wang, et al.Cancer Research|February 12, 2022
A Novel HER2-Selective Kinase Inhibitor Is Effective in HER2 Mutant and Amplified Non-Small Cell Lung CancerJieun Son, Jaebong Jang, Tyler S Beyett, et al.Cell|June 11, 2025
MT-125 inhibits non-muscle myosin IIA and IIB and prolongs survival in glioblastomaRajappa S Kenchappa, Laszlo Radnai, Erica J Young, et al.ACS Chemical Biology|September 24, 2021
Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin IILaszlo Radnai, Matthew Surman, Madalyn Hafenbreidel, et al.Cancer Discovery|May 17, 2019
Single and Dual Targeting of Mutant EGFR with an Allosteric InhibitorCiric To, Jaebong Jang, Ting Chen, et al.Nature Chemical Biology|January 29, 2021
Chemical systems biology reveals mechanisms of glucocorticoid receptor signalingNelson E Bruno, Jerome C Nwachukwu, Sathish Srinivasan, et al.Nature|September 6, 2011
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylationJang Hyun Choi, Alexander S Banks, Theodore M Kamenecka, et al.ACS Chemical Biology|January 21, 2015
Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survivalJae Won Chang, Andrea M Zuhl, Anna E Speers, et al.Pageof 15