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Journal of Biomolecular Screening
|
February 11, 2016
Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5
Michael Finley, Jason Cassaday, Tony Kreamer, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 5, 2022
Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes
Lukas Lercher, Nina Simon, Andreas Bergmann, et al.
Nucleic Acids Research
|
July 4, 2025
Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
Jung-Hoon Lee, Maren Thomsen, Herwin Daub, et al.
Journal of Medicinal Chemistry
|
April 9, 2015
Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)
William H Parsons, Raul R Calvo, Wing Cheung, et al.
ACS Chemical Biology
|
December 30, 2016
Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening
Peter S Kutchukian, Lee Warren, Brian C Magliaro, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 4, 2025
Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors
Gareth N Brace, Karsten Tillack, Peter D Johnson, et al.
Biorxiv : the Preprint Server for Biology
|
July 3, 2026
Mismatch repair dissection by in vivo RNAi reveals dose-dependent modulators of somatic instability and proteome remodeling in Huntington's disease
Jillian Belgrad, Todd M Greco, Ellen Sapp, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 26, 2023
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation
Holger Babbe, Thomas B Sundberg, Mark Tichenor, et al.
EMBO Molecular Medicine
|
December 9, 2024
Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome
Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, et al.
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Showing results (11-20 of 19) with videos related to
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This site can display upto 19 results.
Journal of Biomolecular Screening
|
February 11, 2016
Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5
Michael Finley, Jason Cassaday, Tony Kreamer, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
May 5, 2022
Identification of Two Non-Peptidergic Small Molecule Inhibitors of CBX2 Binding to K27 Trimethylated Oligonucleosomes
Lukas Lercher, Nina Simon, Andreas Bergmann, et al.
Nucleic Acids Research
|
July 4, 2025
Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognition
Jung-Hoon Lee, Maren Thomsen, Herwin Daub, et al.
Journal of Medicinal Chemistry
|
April 9, 2015
Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]-1H-benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)
William H Parsons, Raul R Calvo, Wing Cheung, et al.
ACS Chemical Biology
|
December 30, 2016
Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening
Peter S Kutchukian, Lee Warren, Brian C Magliaro, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 4, 2025
Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitors
Gareth N Brace, Karsten Tillack, Peter D Johnson, et al.
Biorxiv : the Preprint Server for Biology
|
July 3, 2026
Mismatch repair dissection by in vivo RNAi reveals dose-dependent modulators of somatic instability and proteome remodeling in Huntington's disease
Jillian Belgrad, Todd M Greco, Ellen Sapp, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
December 26, 2023
Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation
Holger Babbe, Thomas B Sundberg, Mark Tichenor, et al.
EMBO Molecular Medicine
|
December 9, 2024
Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome
Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, et al.
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