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RSC Chemical Biology|November 3, 2023
A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screeningKayla Nutsch, Lirui Song, Emily Chen, et al.
Journal of the American Chemical Society|November 14, 2024
Scalable Thiol Reactivity Profiling Identifies Azetidinyl Oxadiazoles as Cysteine-Targeting ElectrophilesFereshte Ghorbani, Shaochen You, Gennadii A Grabovyi, et al.
Cell Reports|August 28, 2024
The glycolytic metabolite methylglyoxal covalently inactivates the NLRP3 inflammasomeCaroline Stanton, Chavin Buasakdi, Jie Sun, et al.
ACS Chemical Biology|March 2, 2019
Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA SequencingJulia M D Grandjean, Lars Plate, Richard I Morimoto, et al.
Biorxiv : the Preprint Server for Biology|April 25, 2024
The Glycolytic Metabolite Methylglyoxal Covalently Inactivates the NLRP3 InflammasomeCaroline Stanton, Chavin Buasakdi, Jie Sun, et al.
Biorxiv : the Preprint Server for Biology|May 3, 2023
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2Maya L Bulos, Edyta M Grzelak, Chloris Li-Ma, et al.
ACS Chemical Biology|April 3, 2025
Augmented Acyl-CoA Biosynthesis Promotes Resistance to TEAD Palmitoylation Site InhibitionKayla Nutsch, Marissa N Trujillo, Lirui Song, et al.
Elife|December 21, 2023
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2Maya L Bulos, Edyta M Grzelak, Chloris Li-Ma, et al.
ACS Chemical Biology|November 19, 2021
Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2Jessica D Rosarda, Kelsey R Baron, Kayla Nutsch, et al.
Biorxiv : the Preprint Server for Biology|May 22, 2023
Succinylation of a KEAP1 sensor lysine promotes NRF2 activationLara Ibrahim, Caroline Stanton, Kayla Nutsch, et al.
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