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The AAPS Journal|September 3, 2020
A Physiologically Based Pharmacokinetic Model of Vismodegib: Deconvoluting the Impact of Saturable Plasma Protein Binding, pH-Dependent Solubility and Nonsink PermeationMichael J Dolton, Po-Chang Chiang, Fang Ma, et al.
Antimicrobial Agents and Chemotherapy|September 10, 2014
Understanding variability in posaconazole exposure using an integrated population pharmacokinetic analysisMichael J Dolton, Roger J M Brüggemann, David M Burger, et al.
The Journal of Antimicrobial Chemotherapy|February 21, 2014
Understanding variability with voriconazole using a population pharmacokinetic approach: implications for optimal dosingMichael J Dolton, Gerd Mikus, Johanna Weiss, et al.
Journal of Pharmaceutical Sciences|February 5, 2022
Evaluating the IVIVC by Combining Tiny-tim Outputs and Compartmental PK Model to Predict Oral Exposure for Different Formulations of IbuprofenPo-Chang Chiang, Jia Liu, Karthik Nagapudi, et al.
Antimicrobial Agents and Chemotherapy|August 15, 2012
Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentrationMichael J Dolton, John E Ray, Sharon C-A Chen, et al.
Antimicrobial Agents and Chemotherapy|July 4, 2012
Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoringMichael J Dolton, John E Ray, Sharon C-A Chen, et al.
Journal of Pharmaceutical Sciences|July 13, 2024
Integrating Dynamic in vitro Systems and Mechanistic Absorption Modeling: Case Study of PralsetinibMichael J Dolton, Christine Bowman, Fang Ma, et al.
British Journal of Clinical Pharmacology|April 30, 2014
Optimal sampling of antipsychotic medicines: a pharmacometric approach for clinical practiceVidya Perera, Robert R Bies, Gary Mo, et al.
Neurology|August 29, 2023
Randomized Phase II Study of the Safety and Efficacy of Semorinemab in Participants With Mild-to-Moderate Alzheimer Disease: LaurietCecilia Monteiro, Balazs Toth, Flavia Brunstein, et al.
Clinical Pharmacology and Therapeutics|August 4, 2021
Safety, Tolerability, and Pharmacokinetics of High-Volume Subcutaneous Crenezumab, With and Without Recombinant Human Hyaluronidase in Healthy VolunteersMichael J Dolton, Aaron Chesterman, Anita Moein, et al.
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