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Neuroscience|January 3, 2018
Microglial Priming as Trained Immunity in the BrainMichael J Haley, David Brough, Jessica Quintin, et al.
Trends in Pharmacological Sciences|July 27, 2011
Regulation of interleukin-1 in acute brain injuryDavid Brough, Pippa J Tyrrell, Stuart M Allan
Experimental Physiology|June 23, 2015
Interleukin-1 as a pharmacological target in acute brain injuryDavid Brough, Nancy J Rothwell, Stuart M Allan
The Journal of Biological Chemistry|September 2, 2015
Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 CleavageMichelle E Edye, David Brough, Stuart M Allan
The Journal of Biological Chemistry|September 12, 2013
Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathwayMichelle E Edye, Gloria Lopez-Castejon, Stuart M Allan, et al.
Immunology|February 9, 2022
Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophagesChristopher Hoyle, Jack P Green, Stuart M Allan, et al.
Glia|February 14, 2013
Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen-glucose deprivation in organotypic brain slicesSylvie Girard, David Brough, Gloria Lopez-Castejon, et al.
Biorxiv : the Preprint Server for Biology|March 11, 2024
The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndromeTara A Gleeson, Christina Kaiser, Catherine B Lawrence, et al.
Disease Models & Mechanisms|June 9, 2012
Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathologyAndrew D Greenhalgh, David Brough, Emily M Robinson, et al.
Disease Models & Mechanisms|May 22, 2024
The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndromeTara A Gleeson, Christina Kaiser, Catherine B Lawrence, et al.
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