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Journal of Medicinal Chemistry
|
June 22, 2007
Dual aromatase-steroid sulfatase inhibitors
L W Lawrence Woo, Christian Bubert, Oliver B Sutcliffe, et al.
Breast Cancer Research and Treatment
|
October 5, 2007
Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer
Paul A Foster, Surinder K Chander, Michael F C Parsons, et al.
Organic & Biomolecular Chemistry
|
October 31, 2008
Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling
Fabrice Jourdan, Christian Bubert, Mathew P Leese, et al.
Biochemistry
|
May 4, 2005
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors
Matthew D Lloyd, Nethaji Thiyagarajan, Yaik T Ho, et al.
Bioorganic & Medicinal Chemistry
|
March 11, 2008
Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design
Gillian M Allan, Nigel Vicker, Harshani R Lawrence, et al.
Journal of Medicinal Chemistry
|
February 13, 2010
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
L W Lawrence Woo, Toby Jackson, Aurélien Putey, et al.
Chemmedchem
|
July 16, 2010
Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities
Paul M Wood, L W Lawrence Woo, Jean-Robert Labrosse, et al.
Cancer Research
|
January 7, 2006
The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells
Simon P Newman, Christopher R Ireson, Helena J Tutill, et al.
Endocrine-Related Cancer
|
November 8, 2012
STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model
Joanna M Day, Paul A Foster, Helena J Tutill, et al.
Journal of Medicinal Chemistry
|
December 22, 2006
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity
Mathew P Leese, Bertrand Leblond, Andrew Smith, et al.
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of 8
Search research articles
Search
Showing results (51-60 of 76) with videos related to
Sort By:
Page
of 8
Journal of Medicinal Chemistry
|
June 22, 2007
Dual aromatase-steroid sulfatase inhibitors
L W Lawrence Woo, Christian Bubert, Oliver B Sutcliffe, et al.
Breast Cancer Research and Treatment
|
October 5, 2007
Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer
Paul A Foster, Surinder K Chander, Michael F C Parsons, et al.
Organic & Biomolecular Chemistry
|
October 31, 2008
Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling
Fabrice Jourdan, Christian Bubert, Mathew P Leese, et al.
Biochemistry
|
May 4, 2005
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors
Matthew D Lloyd, Nethaji Thiyagarajan, Yaik T Ho, et al.
Bioorganic & Medicinal Chemistry
|
March 11, 2008
Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design
Gillian M Allan, Nigel Vicker, Harshani R Lawrence, et al.
Journal of Medicinal Chemistry
|
February 13, 2010
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
L W Lawrence Woo, Toby Jackson, Aurélien Putey, et al.
Chemmedchem
|
July 16, 2010
Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities
Paul M Wood, L W Lawrence Woo, Jean-Robert Labrosse, et al.
Cancer Research
|
January 7, 2006
The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells
Simon P Newman, Christopher R Ireson, Helena J Tutill, et al.
Endocrine-Related Cancer
|
November 8, 2012
STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model
Joanna M Day, Paul A Foster, Helena J Tutill, et al.
Journal of Medicinal Chemistry
|
December 22, 2006
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity
Mathew P Leese, Bertrand Leblond, Andrew Smith, et al.
Page
of 8