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Journal of Medicinal Chemistry|April 25, 2022
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain InhibitorDuncan C Miller, Tristan Reuillon, Lauren Molyneux, et al.Journal of Medicinal Chemistry|May 10, 2017
Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic InhibitorsWilliam McCoull, Roman D Abrams, Erica Anderson, et al.Nature Communications|October 8, 2020
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main proteaseAlice Douangamath, Daren Fearon, Paul Gehrtz, et al.ACS Chemical Biology|October 19, 2018
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6William McCoull, Tony Cheung, Erica Anderson, et al.Journal of Medicinal Chemistry|July 2, 2021
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing KinaseIslam Al-Khawaldeh, Mohammed J Al Yasiri, Gregory G Aldred, et al.Journal of Medicinal Chemistry|October 2, 2014
Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptorM Raymond V Finlay, Mark Anderton, Susan Ashton, et al.Pageof 9