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Current Opinion in Cell Biology|January 18, 2020
Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligandsMichael Lückmann, Mette Trauelsen, Thomas M Frimurer, et al.
Cell Metabolism|February 8, 2018
The HETE Is on FFAR1 and Pancreatic Islet CellsMette Trauelsen, Michael Lückmann, Thomas M Frimurer, et al.
Molecular Informatics|August 6, 2016
In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide AgonistMichael Lückmann, Birgitte Holst, Thue W Schwartz, et al.
Nature Communications|June 25, 2024
Multiple recent HCAR2 structures demonstrate a highly dynamic ligand binding and G protein activation modeAslihan Shenol, Ricardo Tenente, Michael Lückmann, et al.
Molecular Cell|February 7, 2024
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91Aslihan Shenol, Michael Lückmann, Mette Trauelsen, et al.
ACS Medicinal Chemistry Letters|December 15, 2022
Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of ActionMichael Lückmann, Aslihan Shenol, Tinne A D Nissen, et al.
Chemmedchem|July 16, 2021
Discovery of GPR183 Agonists Based on an Antagonist ScaffoldViktoria M S Kjaer, Loukas Ieremias, Viktorija Daugvilaite, et al.
Scientific Reports|July 4, 2018
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1Elisabeth Rexen Ulven, Mette Trauelsen, Matjaz Brvar, et al.
British Journal of Pharmacology|April 4, 2017
Biased agonism and allosteric modulation of G protein-coupled receptor 183 - a 7TM receptor also known as Epstein-Barr virus-induced gene 2Viktorija Daugvilaite, Christian Medom Madsen, Michael Lückmann, et al.
The Journal of Biological Chemistry|May 27, 2016
Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule BindingLine Barington, Pia C Rummel, Michael Lückmann, et al.
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