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Biochemistry|May 25, 2011
Loss of allostery and coenzyme B12 delivery by a pathogenic mutation in adenosyltransferaseMichael Lofgren, Ruma Banerjee
The Journal of Biological Chemistry|September 3, 2013
Autoinhibition and signaling by the switch II motif in the G-protein chaperone of a radical B12 enzymeMichael Lofgren, Markos Koutmos, Ruma Banerjee
The Journal of Biological Chemistry|March 30, 2013
Navigating the B(12) road: assimilation, delivery, and disorders of cobalaminCarmen Gherasim, Michael Lofgren, Ruma Banerjee
Nature Chemical Biology|July 23, 2013
A switch III motif relays signaling between a B12 enzyme and its G-protein chaperoneMichael Lofgren, Dominique Padovani, Markos Koutmos, et al.
The Journal of Biological Chemistry|September 9, 2017
Switch I-dependent allosteric signaling in a G-protein chaperone-B12 enzyme complexGregory C Campanello, Michael Lofgren, Adam L Yokom, et al.
Glycobiology|March 24, 2017
Structure of human POFUT1, its requirement in ligand-independent oncogenic Notch signaling, and functional effects of Dowling-Degos mutationsBrian J McMillan, Brandon Zimmerman, Emily D Egan, et al.
Cell Reports. Physical Science|September 15, 2025
Conformation-gated binding underlies kinetic asymmetry and negative cooperativity in ATP:cob(I)alamin adenosyltransferaseGuangjie Yan, Manhua Pan, Aaron M Keller, et al.
Biorxiv : the Preprint Server for Biology|January 20, 2025
Conformation-gated binding drives negative cooperativity in ATP:cob(I)alamin Adenosyltransferase for optimized cobalamin handlingGuangjie Yan, Manhua Pan, Aaron M Keller, et al.
Frontiers in Immunology|June 16, 2025
Membrane-bound IL-15 co-expression powers a potent and persistent CD70-targeted TRuC T-cell therapyLindsay Webb, Michael Lofgren, Troy Patterson, et al.
Cancer Immunology, Immunotherapy : CII|October 17, 2023
Functional enhancement of mesothelin-targeted TRuC-T cells by a PD1-CD28 chimeric switch receptorDerrick McCarthy, Michael Lofgren, Amy Watt, et al.
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