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Cancer Drug Resistance (Alhambra, Calif.)|October 16, 2023
The multidrug resistance transporter P-glycoprotein confers resistance to ferroptosis inducersWilliam J E Frye, Lyn M Huff, José M González Dalmasy, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 10, 2010
N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrierPavitra Kannan, Kyle R Brimacombe, Sami S Zoghbi, et al.
Molecular Cancer Therapeutics|June 2, 2026
A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cellsNisha R Pawar, Heidi M Wade, Zoe Jackson, et al.
Cancer Research|May 3, 2006
Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancerJoseph A Ludwig, Gergely Szakács, Scott E Martin, et al.
Molecular Cancer Therapeutics|July 9, 2009
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery databaseJosiah N Orina, Anna Maria Calcagno, Chung-Pu Wu, et al.
Biochemistry|January 29, 2016
Human-Mouse Chimeras with Normal Expression and Function Reveal That Major Domain Swapping Is Tolerated by P-Glycoprotein (ABCB1)Kristen M Pluchino, Matthew D Hall, Janna K Moen, et al.
Molecular Pharmacology|May 19, 2016
Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic CycleGabriel A Frank, Suneet Shukla, Prashant Rao, et al.
Biochemistry|July 31, 2007
Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membraneJill K Paterson, Suneet Shukla, Chelsea M Black, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 26, 2011
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PETPavitra Kannan, Kyle R Brimacombe, William C Kreisl, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 17, 2006
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomasKevin G Chen, Julio C Valencia, Barry Lai, et al.
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