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Biochemical Pharmacology|August 23, 2018
Cellular pharmacology of evofosfamide (TH-302): A critical re-evaluation of its bystander effectsCho Rong Hong, Benjamin D Dickson, Jagdish K Jaiswal, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|June 7, 2013
18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft modelSatish K Chitneni, Gerald T Bida, Hong Yuan, et al.Cancers|December 16, 2020
Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck CancerTet Woo Lee, Amy Lai, Julia K Harms, et al.Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology|December 3, 2021
Radiosensitisation of SCCVII tumours and normal tissues in mice by the DNA-dependent protein kinase inhibitor AZD7648Cho R Hong, Chantal D Buckley, Way W Wong, et al.Journal of the National Cancer Institute|August 17, 2006
Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugsKevin O Hicks, Frederik B Pruijn, Timothy W Secomb, et al.Journal of Medicinal Chemistry|December 28, 2002
Structure-activity relationships of 1,2,4-benzotriazine 1,4-dioxides as hypoxia-selective analogues of tirapazamineMichael P Hay, Swarna A Gamage, Mary S Kovacs, et al.Molecules (Basel, Switzerland)|July 13, 2019
Benzotriazine Di-Oxide Prodrugs for Exploiting Hypoxia and Low Extracellular pH in TumorsMichael P Hay, Hong Nam Shin, Way Wua Wong, et al.Journal of Medicinal Chemistry|December 7, 2007
Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activityMichael P Hay, Karin Pchalek, Frederik B Pruijn, et al.Journal of Medicinal Chemistry|October 14, 2008
Tricyclic [1,2,4]triazine 1,4-dioxides as hypoxia selective cytotoxinsMichael P Hay, Kevin O Hicks, Karin Pchalek, et al.Biochemical Pharmacology|September 22, 2019
Hypoxia-selective radiosensitisation by SN38023, a bioreductive prodrug of DNA-dependent protein kinase inhibitor IC87361Way Wua Wong, Rosanna K Jackson, Lydia P Liew, et al.Pageof 7