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Michael P Pollastri

Showing results (21-30 of 67) with videos related to

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European Journal of Medicinal Chemistry|August 15, 2012
The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposingStefan O Ochiana, Vidya Pandarinath, Zhouxi Wang, et al.
Bioconjugate Chemistry|May 22, 2023
Synthesis of a DNA-Encoded Macrocyclic Library Utilizing Intramolecular Benzimidazole FormationJing Chai, Christopher C Arico-Muendel, Yun Ding, et al.
Plos Neglected Tropical Diseases|September 16, 2017
The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug targetStefan Kunz, Vreni Balmer, Geert Jan Sterk, et al.
Bioorganic & Medicinal Chemistry Letters|March 2, 2012
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogsStefan O Ochiana, Alden Gustafson, Nicholas D Bland, et al.
Molecular Pharmacology|May 23, 2022
Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug DevelopmentCarlos E Sanz-Rodríguez, Benjamin Hoffman, Paul J Guyett, et al.
Bioorganic & Medicinal Chemistry Letters|February 29, 2012
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogsCuihua Wang, Trent D Ashton, Alden Gustafson, et al.
Medchemcomm|June 10, 2014
Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discoveryGautam Patel, Norma E Roncal, Patricia J Lee, et al.
ACS Medicinal Chemistry Letters|September 17, 2025
Optimization of Quinazolines for Inhibition of <i>Trypanosoma brucei</i> ProliferationSam Spijkers-Shaw, Pradip K Gadekar, Baljinder Singh, et al.
Plos Neglected Tropical Diseases|September 5, 2014
A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodesBrendan D Galvin, Zhiru Li, Estelle Villemaine, et al.
Journal of Medicinal Chemistry|April 20, 2013
Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasisGautam Patel, Caitlin E Karver, Ranjan Behera, et al.
Pageof 7

Showing results (21-30 of 67) with videos related to

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Pageof 7
European Journal of Medicinal Chemistry|August 15, 2012
The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposingStefan O Ochiana, Vidya Pandarinath, Zhouxi Wang, et al.
Bioconjugate Chemistry|May 22, 2023
Synthesis of a DNA-Encoded Macrocyclic Library Utilizing Intramolecular Benzimidazole FormationJing Chai, Christopher C Arico-Muendel, Yun Ding, et al.
Plos Neglected Tropical Diseases|September 16, 2017
The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug targetStefan Kunz, Vreni Balmer, Geert Jan Sterk, et al.
Bioorganic & Medicinal Chemistry Letters|March 2, 2012
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogsStefan O Ochiana, Alden Gustafson, Nicholas D Bland, et al.
Molecular Pharmacology|May 23, 2022
Physiologic Targets and Modes of Action for CBL0137, a Lead for Human African Trypanosomiasis Drug DevelopmentCarlos E Sanz-Rodríguez, Benjamin Hoffman, Paul J Guyett, et al.
Bioorganic & Medicinal Chemistry Letters|February 29, 2012
Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 1. Sildenafil analogsCuihua Wang, Trent D Ashton, Alden Gustafson, et al.
Medchemcomm|June 10, 2014
Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discoveryGautam Patel, Norma E Roncal, Patricia J Lee, et al.
ACS Medicinal Chemistry Letters|September 17, 2025
Optimization of Quinazolines for Inhibition of <i>Trypanosoma brucei</i> ProliferationSam Spijkers-Shaw, Pradip K Gadekar, Baljinder Singh, et al.
Plos Neglected Tropical Diseases|September 5, 2014
A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodesBrendan D Galvin, Zhiru Li, Estelle Villemaine, et al.
Journal of Medicinal Chemistry|April 20, 2013
Kinase scaffold repurposing for neglected disease drug discovery: discovery of an efficacious, lapatinib-derived lead compound for trypanosomiasisGautam Patel, Caitlin E Karver, Ranjan Behera, et al.
Pageof 7