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Journal of Medicinal Chemistry
|
December 20, 2018
Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development
Kelly A Bachovchin, Amrita Sharma, Seema Bag, et al.
Molecular Pharmacology
|
August 28, 2014
In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo
Ashley J Parks, Michael P Pollastri, Mark E Hahn, et al.
Journal of Medicinal Chemistry
|
November 1, 2019
Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics
Dana M Klug, Laura Tschiegg, Rosario Diaz, et al.
Journal of Medicinal Chemistry
|
October 26, 2011
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness
Nicholas D Bland, Cuihua Wang, Craig Tallman, et al.
Plos Neglected Tropical Diseases
|
October 24, 2014
Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign
Rosario Diaz, Sandra A Luengo-Arratta, João D Seixas, et al.
Plos Neglected Tropical Diseases
|
February 9, 2019
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents
Dana M Klug, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, et al.
Journal of Medicinal Chemistry
|
December 18, 2019
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-<i>b</i>]pyridazines for the Treatment of Human African Trypanosomiasis
Westley F Tear, Seema Bag, Rosario Diaz-Gonzalez, et al.
ACS Infectious Diseases
|
July 7, 2023
Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis
Maria Dichiara, Quillon J Simpson, Antonio Quotadamo, et al.
Journal of Medicinal Chemistry
|
August 13, 2024
Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of <i>Trypanosoma brucei</i>
Lori Ferrins, Rosario Diaz, Carlos Cordon-Obras, et al.
Journal of Medicinal Chemistry
|
September 20, 2025
Optimization of Physicochemical Properties and ADME for 2,4-Substituted 1<i>H</i>-Pyrrolo[2,3<i>b</i>]pyridines Inhibitors of Trypanosome Proliferation
Kelly A Bachovchin, Rosario Díaz, Gloria Ceballos-Perez, et al.
Page
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Search research articles
Search
Showing results (51-60 of 67) with videos related to
Sort By:
Page
of 7
Journal of Medicinal Chemistry
|
December 20, 2018
Improvement of Aqueous Solubility of Lapatinib-Derived Analogues: Identification of a Quinolinimine Lead for Human African Trypanosomiasis Drug Development
Kelly A Bachovchin, Amrita Sharma, Seema Bag, et al.
Molecular Pharmacology
|
August 28, 2014
In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo
Ashley J Parks, Michael P Pollastri, Mark E Hahn, et al.
Journal of Medicinal Chemistry
|
November 1, 2019
Hit-to-Lead Optimization of Benzoxazepinoindazoles As Human African Trypanosomiasis Therapeutics
Dana M Klug, Laura Tschiegg, Rosario Diaz, et al.
Journal of Medicinal Chemistry
|
October 26, 2011
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness
Nicholas D Bland, Cuihua Wang, Craig Tallman, et al.
Plos Neglected Tropical Diseases
|
October 24, 2014
Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign
Rosario Diaz, Sandra A Luengo-Arratta, João D Seixas, et al.
Plos Neglected Tropical Diseases
|
February 9, 2019
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents
Dana M Klug, Rosario Diaz-Gonzalez, Guiomar Pérez-Moreno, et al.
Journal of Medicinal Chemistry
|
December 18, 2019
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-<i>b</i>]pyridazines for the Treatment of Human African Trypanosomiasis
Westley F Tear, Seema Bag, Rosario Diaz-Gonzalez, et al.
ACS Infectious Diseases
|
July 7, 2023
Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis
Maria Dichiara, Quillon J Simpson, Antonio Quotadamo, et al.
Journal of Medicinal Chemistry
|
August 13, 2024
Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of <i>Trypanosoma brucei</i>
Lori Ferrins, Rosario Diaz, Carlos Cordon-Obras, et al.
Journal of Medicinal Chemistry
|
September 20, 2025
Optimization of Physicochemical Properties and ADME for 2,4-Substituted 1<i>H</i>-Pyrrolo[2,3<i>b</i>]pyridines Inhibitors of Trypanosome Proliferation
Kelly A Bachovchin, Rosario Díaz, Gloria Ceballos-Perez, et al.
Page
of 7