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Journal of Medicinal Chemistry|March 29, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3<i>H</i>)-quinazolinone Aryl Urea pan-RAF Kinase InhibitorMalcolm P Huestis, Darlene Dela Cruz, Antonio G DiPasquale, et al.Bioorganic & Medicinal Chemistry Letters|July 23, 2013
2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitorsMichael Siu, Richard Pastor, Wendy Liu, et al.Microbiology Spectrum|October 6, 2021
Averting an Outbreak of SARS-CoV-2 in a University Residence Hall through Wastewater SurveillanceRyland Corchis-Scott, Qiudi Geng, Rajesh Seth, et al.Bioorganic & Medicinal Chemistry Letters|March 16, 2013
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: strategies to eliminate reactive metabolitesSajiv K Nair, Jean J Matthews, Stephan J Cripps, et al.Bioorganic & Medicinal Chemistry Letters|June 4, 2011
Structure-based design of thienobenzoxepin inhibitors of PI3-kinaseSteven T Staben, Michael Siu, Richard Goldsmith, et al.Journal of Medicinal Chemistry|October 30, 2025
Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory DiseasesSnahel Patel, Huifen Chen, Eugene Varfolomeev, et al.Journal of Medicinal Chemistry|November 15, 2021
Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase InhibitorsDennis X Hu, Snahel Patel, Huifen Chen, et al.Journal of Medicinal Chemistry|November 21, 2014
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitorsAllen A Thomas, Kevin W Hunt, Brad Newhouse, et al.Clinical Proteomics|January 2, 2019
The plasma peptides of ovarian cancerJaimie Dufresne, Pete Bowden, Thanusi Thavarajah, et al.ACS Medicinal Chemistry Letters|September 18, 2024
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1John C Tellis, BinQing Wei, Michael Siu, et al.Pageof 22