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Toxicology Letters|July 16, 2023
Off target toxicities and links with physicochemical properties of medicinal products, including antibiotics, oligonucleotides, lipid nanoparticles (with cationic and/or anionic charges). Data review suggests an emerging patternSarah Gould, Michael V Templin
Therapeutic Delivery|July 28, 2012
Delivery and biodistribution of siRNA for cancer therapy: challenges and future prospectsShaguna Seth, Rachel Johns, Michael V Templin
Methods in Molecular Biology (Clifton, N.J.)|March 11, 2010
A potential therapeutic for pandemic influenza using RNA interferenceShaguna Seth, Michael V Templin, Gregory Severson, et al.
Birth Defects Research. Part B, Developmental and Reproductive Toxicology|February 24, 2006
Maternal and fetal distribution of a phosphorothioate oligonucleotide in rats after intravenous infusionNicole V Soucy, Jason P Riley, Michael V Templin, et al.
Antiviral Therapy|October 9, 2008
Inhibition of human metapneumovirus replication by small interfering RNACéline Deffrasnes, Marie-Hélène Cavanagh, Nathalie Goyette, et al.
Expert Opinion on Drug Discovery|November 21, 2022
RNA-based drug discovery for spinal muscular atrophy: a story of small molecules and antisense oligonucleotidesBlanca Torroba, Natsuko Macabuag, Elisabeth M Haisma, et al.
Inhalation Toxicology|June 17, 2014
Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkeyRobert A Fey, Michael V Templin, Jacob D McDonald, et al.
Nucleic Acids Research|November 5, 2010
Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogsNarendra Vaish, Feng Chen, Shaguna Seth, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|April 21, 2011
An amino acid-based amphoteric liposomal delivery system for systemic administration of siRNARoger C Adami, Shaguna Seth, Pierrot Harvie, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|March 3, 2011
RNAi-based therapeutics targeting survivin and PLK1 for treatment of bladder cancerShaguna Seth, Yoshiyuki Matsui, Kathy Fosnaugh, et al.
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