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Proceedings of the National Academy of Sciences of the United States of America|January 3, 2023
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritisYuqing Wang, Duolong Zhu, Laura C Ortiz-Velez, et al.Frontiers in Pharmacology|October 11, 2021
Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple SclerosisIoannis Markakis, Ioannis Charitakis, Christine Beeton, et al.Plos One|October 23, 2013
Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytesShyny Koshy, Danli Wu, Xueyou Hu, et al.The Journal of Biological Chemistry|June 20, 2003
The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sitesAlexei F Kisselev, Margarita Garcia-Calvo, Herman S Overkleeft, et al.Scientific Reports|June 18, 2017
Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental ratsRalf Bergmann, Manja Kubeil, Kristof Zarschler, et al.Toxicon : Official Journal of the International Society on Toxinology|May 18, 2018
Synthesis, folding, structure and activity of a predicted peptide from the sea anemone Oulactis sp. with an ShKT foldBankala Krishnarjuna, Jessica Villegas-Moreno, Michela L Mitchell, et al.Glia|June 12, 2020
Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microgliaHai M Nguyen, Jacopo di Lucente, Yi-Je Chen, et al.Clinical Immunology (Orlando, Fla.)|April 9, 2017
Prolonged immunomodulation in inflammatory arthritis using the selective Kv1.3 channel blocker HsTX1[R14A] and its PEGylated analogMark R Tanner, Rajeev B Tajhya, Redwan Huq, et al.Plos One|November 19, 2013
A potent and selective peptide blocker of the Kv1.3 channel: prediction from free-energy simulations and experimental confirmationM Harunur Rashid, Germano Heinzelmann, Redwan Huq, et al.The Journal of Biological Chemistry|November 7, 2007
The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferationChristine Beeton, Brian J Smith, Jennifer K Sabo, et al.Pageof 6